ReviewFuture medicinal chemistry2025
Thiazole derivatives in cancer therapy: mechanistic insights, bioactivity, and future perspective.
Review in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Thiazole as a Promising Scaffold for the Treatment of Schistosomiasis: In Vitro and In Vivo Activity Against Different Developmental Stages ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Adamantane-thiazole hybrids and related derivatives: synthesis, crystal structures, in vitro antibacterial, antifungal, and anti-proliferative activities.BMC chemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Globally, cancer is the primary cause of both mortality and morbidity. Many researchers are working to create new anticancer drugs that are less harmful and more effective. A thiazole scaffold is a great option for developing compounds that interact with cancer target locations and block the biological pathways causing the disease to spread. The current state of thiazole-based anticancer medicines is highlighted in this review, along with recent research findings. The thiazole moiety is an eccentric building block for creating anticancer medications. Thiazole derivatives have a great pharmacological profile that targets a variety of proteins and enzymes. The thiazoles are highlighted by the nitrogen atom's ability to establish hydrogen bonds with their targets. Thiazole has been shown in numerous clinical trials to be useful in treating cancer by acting through a variety of routes. Research on thiazole derivatives for cancer treatment featuring a superior pharmacokinetic profile is encouraged by the approval of thiazole-based medications for use as chemotherapeutics, such as Dasatinib and Ixazomib. This led to the consideration of thiazole derivatives as anticancer drugs to identify possible derivatives that are currently being investigated. This review covers research on thiazole scaffolds with anti-cancer potential both
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.