Evidence map›Paper›PMID 40874615›Full record

ArticlemBio2025

Disruptions in outer membrane-peptidoglycan interactions enhance bile salt resistance in O-antigen-producing

Jilong Qin, Yaoqin Hong, Waldemar Vollmer, Renato Morona, Makrina Totsika

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Peptidoglycan LD-Transpeptidases.Antibiotics (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jilong QinCentre for Immunology and Infection Control, School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0002-5867-6332
Yaoqin HongCentre for Immunology and Infection Control, School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0002-4408-2648
Waldemar VollmerInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0003-0408-8567
Renato MoronaSchool of Biological Sciences, Department of Molecular & Biomedical Sciences, Research Centre for Infectious Diseases, University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0001-7009-7440
Makrina TotsikaCentre for Immunology and Infection Control, School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0003-2468-0293

Funding

Australian Research Council DP210101317Queensland University of Technology ECRIG2024
6 · The paper itself

Abstract

Bile salts (BS) are antimicrobials that disrupt bacterial cell membranes and induce oxidative stress. The gut bacterium

Indexed as

Bacterial Outer MembraneBile Acids and SaltsDrug Resistance, BacterialEscherichia coliEscherichia coli K12O AntigensPeptidoglycanBacterial Outer Membrane ProteinsEscherichia coli ProteinsLipopolysaccharidesMutationBacterial Outer Membrane ProteinsBile Acids and SaltsEscherichia coli ProteinsLipopolysaccharidesO AntigensPeptidoglycancell envelopeLppO antigenOmpApeptidoglycanpolysaccharides

Identifiers

PMID40874615
PMCPMC12505904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.