Evidence map›Paper›PMID 40874607›Full record

ArticlemSphere2025

Establishing an

E C Townsend, K Xu, K De La Cruz, L Huang, S Sandstrom, J J Meudt, D Shanmuganayagam, A Huttenlocher, A L F Gibson, L R Kalan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

E C TownsendDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0003-3102-8033
K XuDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
K De La CruzDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
L HuangDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
S SandstromDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
J J MeudtDepartment of Animal & Dairy Sciences, University of Wisconsin, Madison, Wisconsin, USA.
D ShanmuganayagamDepartment of Animal & Dairy Sciences, University of Wisconsin, Madison, Wisconsin, USA.
A HuttenlocherDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
A L F GibsonDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
L R KalanDepartment of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0003-4980-5128

Funding

Elucidating the Role of Microbial Community Dynamics in Wound Repair and RegenerationR35GM137828 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KALAN, LINDSAY ROBYN · 2020 to 2021
$750k
NIGMS NIH HHS R35 GM137828NIH HHS R35GM137828
6 · The paper itself

Abstract

Incomplete antiseptic efficacy against potentially pathogenic microbial taxa places some patients at disproportionate risk for developing a surgical site infection. Laboratory models capable of interrogating the effects of antiseptics on the skin and its complex microbial communities are desperately needed to improve and better tailor antiseptic formulations. This work aims to establish an IMPORTANCE: Broad-spectrum antiseptics are widely used to prevent surgical site infection and as wound cleansing agents. The impacts of such agents on beneficial microbes in the skin microbiome are understudied. Here, we describe an

Indexed as

Anti-Infective Agents, LocalBacteriaMicrobiotaSkinAnimalsChlorhexidineMicrobial ViabilityRNA, Ribosomal, 16SSwineAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconateRNA, Ribosomal, 16Santisepticschlorhexidine gluconateskin microbiomeviability PCR

Identifiers

PMID40874607
PMCPMC12482178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.