Evidence map›Paper›PMID 40874346›Full record

ArticleHaematologica2026

Benchmarking prophylaxis with factor concentrates: reference data on annualized bleeding rates in children with severe hemophilia.

Susanna Ranta, Marloes De Kovel, Martin Olivieri, Kathelijn Fischer, Giancarlo Castaman, Christoph Königs, Johannes Oldenburg, Helen Pergantou, Christoph Male, Marijke H Van den Berg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. When and How to Start Prophylaxis in Children with Hemophilia.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Review
  2. The Swiss Haemophilia Registry-Report From the First 8 Years.Haemophilia : the official journal of the World Federation of Hemophilia
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Susanna RantaPediatric Coagulation Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Department of Women's and Children's Health, Karolinska Institutet, Stockholm. susanna.ranta@ki.se.
Marloes De KovelPedNet Hemophilia Research Foundation, Baarn.
Martin OlivieriPediatric thrombosis and Hemostasis Unit, Pediatric Hemophilia Centre, Dr. von Hauner Children's Hospital LMU Munich.
Kathelijn FischerPedNet Hemophilia Research Foundation, Baarn, the Netherlands; Center for Benign Haematology, Thrombosis and Haemostasis Van Creveldkliniek, University Medical Center Utrecht, Utrecht.
Giancarlo CastamanCenter for Bleeding Disorders and Coagulation, Department of Heart, Lung and Vessels, Careggi University Hospital, Florence.
Christoph KönigsGoethe University, University Hospital Frankfurt, Department of Paediatrics and Adolescent Medicine.
Johannes OldenburgInstitute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Medical Faculty, University of Bonn.
Helen PergantouHaemophilia Centre/Haemostasis and Thrombosis Unit, Aghia Sophia Children's Hospital, Athens-Greece.
Christoph MaleDepartment of Paediatrics, Medical University Hospital of Vienna, Vienna.
Marijke H Van den BergPedNet Hemophilia Research Foundation, Baarn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40874346
PMCPMC12862299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.