ArticleRSC advances2025
Silver-zinc oxide-doped hydroxyapatite nanocomposite: an efficient peroxidase nanozyme for the colorimetric detection of ascorbic acid.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Next generation smart functionalized nanocomposites for ultrasensitive and real time detection of purine derived metabolic biomarkers.RSC advances · 2026Review
- Plant-dependent and pH-responsive FeRSC advances · 2026Article
- Matrix-tolerant dual-route detection of antioxidants and nitrite using gold nanorod cascade etching with localized surface plasmon resonance and photothermal readouts.Mikrochimica acta · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ascorbic acid is an important player in the food and pharmaceutical industries and plays a key role in the human body. Its abnormal concentration is linked to pathological conditions and monitoring the quality of food and pharmaceutical products. Therefore, it is necessary to monitor its concentration through reliable platforms that are easy to use and affordable. The current work reports a new silver and zinc oxide-doped hydroxyapatite (Ag-ZnO@HAp) nanocomposite based colorimetric sensor prepared using a waste valorization approach through a salt-melting method. The synthesis of the nanocomposite was validated through multiple spectroscopic and morphological techniques, which confirmed the desired synthesis. The synthesized nanozyme was able to act as a peroxidase mimic in the presence of hydrogen peroxide. This activity of the nanozyme resulted in the oxidation of tetramethylbenzidine (TMB) to a blue-green oxTMB. Introduction of the analyte to the system transformed the blue-green color of oxTMB to a colorless form. Various variables affecting the efficiency of the proposed sensor were optimized, and the optimized conditions were reported to be 5 mg of the nanozyme, 4 mM TMB, 18 mM H
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Registered trials
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