ReviewFrontiers in neuroscience2025
Affective-cognitive circuits in postoperative appetite reduction: an adaptive neuroimmune response to surgical stress.
Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The Symptom Clusters and Core Symptoms in Patients with Lung Cancer After Surgery: A Longitudinal Network Analysis.Patient preference and adherence · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative reduction in appetite perception, conceptualized as an interplay between emotion, perception, and cognition, may lead to adverse nutritional outcomes. However, an increasing body of research suggests that it may serve as an adaptive mechanism to inhibit inflammatory responses and regulate metabolic burden. This review comprehensively summarizes the multifaceted mechanisms underlying postoperative changes in appetite perception, particularly from the perspectives of immune regulation, inflammatory suppression, and metabolic reprogramming. Special attention is paid to the affective and cognitive dimensions of appetite perception, exploring how emotion-related processing and neurocognitive feedback contribute to appetite perception suppression during recovery. Moreover, this review highlights the clinical significance of these affective-perceptual changes in postoperative nutritional management, emphasizing the need to integrate psychological, perceptual, and neuroimmune factors into patient care strategies. Ultimately, the article explores the potential role of postoperative appetite perception reduction in modulating insulin sensitivity and improving systemic metabolic health. Based on current literature, we advocate for reevaluating appetite perception dynamics during recovery to provide novel theoretical foundations and practical directions for targeted postoperative nutritional interventions.
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