Evidence map›Paper›PMID 40874038›Full record

ArticleThe Southern African journal of critical care : the official journal of the Critical Care Society2025

Ventilation distribution in mechanically ventilated children in response to positioning: An exploratory study.

A Lupton-Smith, A Argent, B Morrow

Abstract read
In one paragraph

Article in The Southern African journal of critical care : the official journal of the Critical Care Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A Lupton-SmithDivision of Physiotherapy, Department of Health and Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-5753-1625
A ArgentDepartment of Paediatrics and Child Health, Faculty of Health Sciences, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0001-9333-2036
B MorrowDepartment of Paediatrics and Child Health, Faculty of Health Sciences, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0001-5193-918X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Traditionally, it was understood that children universally show greater ventilation of the non-dependent lung. Recent studies have questioned the understanding of ventilation distribution patterns in the paediatric population. There are no studies examining the effect of body position in mechanically ventilated infants/children. Objectives: To determine the effect of body position on regional ventilation distribution in mechanically ventilated children. Methods: Thoracic electrical impedance tomography (EIT) measurements were taken in left- and right-side lying, supine and prone positions in mechanically ventilated infants/children. Functional EIT images were produced, and regional relative tidal impedance (ΔZ) in the left, right, ventral and dorsal lung regions was calculated. The proportion of ventilation occurring in large lung regions and regional filling were also calculated. Results: Seventeen children (n=8; 47% male) aged 6 months - 6 years are presented. Many of the children (n=8; 47%) consistently showed greater ventilation in the right lung in both side-lying positions, and in the dorsal lung region (n=6; 35%) in both the supine and prone positions. Regional filling was similar between lung regions in the different body positions. Conclusion: Ventilation distribution in mechanically ventilated infants/children with mild lung disease is variable and similar to that of healthy spontaneously breathing infants/children. Contribution of the study: Ventilation distribution in mechanically ventilated children with mild disease is not dissimilar to that in healthy infants and children. Positioning to optimise ventilation should be tailored to each child's responses. This study provides exploratory data describing ventilation distribution in mechanically ventilated infants and children. These data can be used to inform further research study design.

Indexed as

body positioningelectrical impedance tomographyinfants/childrenmechanical ventilationPaediatric critical careventilation distribution

Identifiers

PMID40874038
PMCPMC12378363

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