Evidence map›Paper›PMID 40873966›Full record

ArticleFood science & nutrition2025

Occurrence of Melamine and Cyanuric Acid in Breast Milk: A Risk Assessment for Infants Aged 0-6 Months.

Leila Nezamoleslami, Arash Ghoorchian, Nishtman Zamani, Tayyebeh Madrakian, Amin Sharifi, Arezo Kavee, Mitra Javdan, Vahid Ghasemzadeh-Mohammadi

Abstract read
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Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leila NezamoleslamiDepartment of Nutrition and Food Hygiene, School of Medicine Hamadan University of Medical Sciences Hamadan Iran.
Arash GhoorchianDepartment of Chemistry Research Center for Development of Advanced Technologies Tehran Iran.
Nishtman ZamaniDepartment of Nutrition and Food Hygiene, School of Medicine Hamadan University of Medical Sciences Hamadan Iran.
Tayyebeh MadrakianDepartment of Analytical Chemistry, Faculty of Chemistry and Petroleum Sciences Bu-Ali Sina University Hamedan Iran.
Amin SharifiDepartment of Nutrition and Food Hygiene, School of Medicine Hamadan University of Medical Sciences Hamadan Iran.
Arezo KaveeDeputy Minister of Health Hamadan University of Medical Sciences Hamadan Iran.
Mitra JavdanDeputy Minister of Health Hamadan University of Medical Sciences Hamadan Iran.
Vahid Ghasemzadeh-MohammadiDepartment of Nutrition and Food Hygiene, School of Medicine Hamadan University of Medical Sciences Hamadan Iran.ORCID https://orcid.org/0000-0002-1858-3297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melamine (MEL) and cyanuric acid (CYA) are contaminants that can enter the human body through dietary sources, raising significant toxicological concerns, particularly for infants. MEL undergoes minimal biotransformation in the human body. While breast milk is widely recognized as the optimal source of nutrition for infants, it may also serve as a potential route for the transmission of contaminants. This study aimed to quantify the concentrations of MEL and CYA in breast milk and assess the associated non-carcinogenic toxicity risks for infants aged 0-6 months. A total of 100 mothers from Hamadan, Iran, who exclusively breastfed their infants aged 15-150 days, were included. Breast milk samples, ranging from 10 to 50 mL, were manually expressed. The results revealed that 77% of the samples contained MEL, while 84% contained CYA, both exceeding the detection limits. The average concentrations of MEL and CYA were 730 ± 26 and 400 ± 38 ng mL

Identifiers

PMID40873966
PMCPMC12378073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.