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ArticleHealth science reports2025

Circulation of Measles Virus Genotype B3 in the Republic of the Congo Between 2023 and 2024: A Molecular Characterization Study.

Yanne Vanessa Thiécesse Mavoungou, Matthieu Fritz, Pembe Issamou Mayengue, Félix Koussounda Koukouikila, Igor Judicael Louzolo, Léa Gwladis Ngangoué, Léadisaelle Hosanna Lenguiya, Gabriel Ahombo, Christelle Butel, Laetitia Serrano and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yanne Vanessa Thiécesse MavoungouLaboratoire National de Santé Publique Brazzaville Republic of the Congo.
Matthieu FritzTransVIHMI, Université de Montpellier, INSERM, IRD Montpellier France.ORCID https://orcid.org/0000-0003-4112-3755
Pembe Issamou MayengueLaboratoire National de Santé Publique Brazzaville Republic of the Congo.
Félix Koussounda KoukouikilaLaboratoire National de Santé Publique Brazzaville Republic of the Congo.
Igor Judicael LouzoloLaboratoire National de Santé Publique Brazzaville Republic of the Congo.
Léa Gwladis NgangouéLaboratoire National de Santé Publique Brazzaville Republic of the Congo.
Léadisaelle Hosanna LenguiyaLaboratoire National de Santé Publique Brazzaville Republic of the Congo.
Gabriel AhomboFaculté des Sciences et Techniques Université Marien NGOUABI Brazzaville Republic of the Congo.
Christelle ButelTransVIHMI, Université de Montpellier, INSERM, IRD Montpellier France.
Laetitia SerranoTransVIHMI, Université de Montpellier, INSERM, IRD Montpellier France.
Martine PeetersTransVIHMI, Université de Montpellier, INSERM, IRD Montpellier France.
Eric M LeroyTransVIHMI, Université de Montpellier, INSERM, IRD Montpellier France.
Fabien Roch NiamaLaboratoire National de Santé Publique Brazzaville Republic of the Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: The only previous sequence report of measles virus from the Republic of the Congo (RoC) dates back to samples collected in 2000. To update the molecular epidemiology of measles virus in the RoC, our study genotyped measles virus strains circulating in the country from January 2023 to May 2024. Methods: A total of 584 serum or plasma samples were collected by the National Laboratory of Public Health through its nationwide measles surveillance activities. Among these 584 suspected cases, 231 were IgM seropositive, and 170 of them were selected for molecular detection based on their collection date. Results: Of these, 20 cases were RT-qPCR positive, and six sequences were suitable for sequence analysis. Phylogenetic analysis confirmed that the detected measles virus belongs to genotype B3, which is one of the two genotypes currently circulating globally, alongside genotype D8. Genetic comparison revealed three closely related variants, suggesting either ongoing endemic transmission or potential importation. Notably, 45% of PCR-positive samples had received two vaccine doses, highlighting the need for robust vaccine efficacy evaluation. Conclusion: This study emphasizes the critical role of measles virus surveillance, genotyping capacities, and genetic characterization to strengthen regional disease monitoring and containment strategies.

Indexed as

Central Africaepidemiologygenotypingmeasles virusRepublic of the Congo

Identifiers

PMID40873887
PMCPMC12379835

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.