Evidence map›Paper›PMID 40873881›Full record

ArticleCentral European journal of urology2025

Comparison of the microbiome of bladder urine, upper urinary tract urine, and kidney stones in patients with urolithiasis.

Joanna Chorbińska, Wojciech Krajewski, Paweł Karpiński, Łukasz Nowak, Wojciech Tomczak, Jan Łaszkiewicz, Katarzyna Pacyga-Prus, Sabina Górska, Bartosz Małkiewicz, Tomasz Szydełko

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Article in Central European journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joanna ChorbińskaDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Poland.
Wojciech KrajewskiDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Poland.
Paweł KarpińskiDepartment of Genetics, Wroclaw Medical University, Poland.
Łukasz NowakDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Poland.
Wojciech TomczakDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Poland.
Jan ŁaszkiewiczDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Poland.
Katarzyna Pacyga-PrusLaboratory of Microbiome Immunobiology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Sabina GórskaLaboratory of Microbiome Immunobiology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.
Bartosz MałkiewiczDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Poland.
Tomasz SzydełkoUniversity Center of Excellence in Urology, Wroclaw Medical University, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: It is believed that bacteria can be involved in the formation of all types of stones. The aim of study was to assess the urinary microbiome in patients with urolithiasis. Material and methods: The study group included 50 patients qualified for endoscopic treatment of urinary tract stones using: ureteroscopic lithotripsy (URSL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotripsy (PCNL), endoscopic combined intrarenal surgery (ECIRS). Before the procedure, patients were asked to collect urine and stool for analysis. Urine from the upper urinary tract and stone fragments were collected intraoperatively. The research material was subjected to 16S rRNA sequencing. The chemical composition of stones was assessed using Raman spectroscopy. Results: In the urinary bladder, upper urinary tract, and kidney stone microbiomes of patients with urolithiasis the predominant bacteria identified were: Conclusions: The microbiome of stones differs from the microbiome of urine, which may play a role in the pathogenesis of urolithiasis. Bladder urine and upper urinary tract urine microbiomes do not differ. Therefore, bladder urine can replace upper urinary tract urine in microbiome studies.

Indexed as

16S rRNA sequencingkidney stonesmicrobiomeurolithiasis

Identifiers

PMID40873881
PMCPMC12379818

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