Evidence map›Paper›PMID 40873853›Full record

ArticleJournal of biomedical optics2025

Monte Carlo simulation platform for laser Doppler flowmetry.

David Thompson, Wietske Verveld, Guillaume Lajoinie, Michel Versluis, Wiendelt Steenbergen, Nienke Bosschaart

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David ThompsonUniversity of Twente, TechMed Centre, Biomedical Photonic Imaging Group, Enschede, The Netherlands.
Wietske VerveldUniversity of Twente, TechMed Centre, Biomedical Photonic Imaging Group, Enschede, The Netherlands.ORCID https://orcid.org/0009-0006-3524-121X
Guillaume LajoinieUniversity of Twente, TechMed Centre, Physics of Fluids Group, Enschede, The Netherlands.
Michel VersluisUniversity of Twente, TechMed Centre, Physics of Fluids Group, Enschede, The Netherlands.ORCID https://orcid.org/0000-0002-2296-1860
Wiendelt SteenbergenUniversity of Twente, TechMed Centre, Biomedical Photonic Imaging Group, Enschede, The Netherlands.ORCID https://orcid.org/0000-0003-3452-6791
Nienke BosschaartUniversity of Twente, TechMed Centre, Biomedical Photonic Imaging Group, Enschede, The Netherlands.ORCID https://orcid.org/0000-0001-9232-1079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Monte Carlo simulation of light propagation in turbid media is important in biomedical optics. Most existing platforms simulate light-tissue interactions in backscattering and planar geometries and are voxel-based, which limits their ability to model curved boundaries accurately. Few platforms incorporate Doppler shifts from flowing media, and they allow limited customization of flow profiles and scattering properties. Although laser Doppler flowmetry (LDF) is common in backscattering-based tissue measurements or low-scattering through-transmission setups, the intermediate case of through-transmission measurements in more scattering samples is underexplored. This case is relevant for applications such as flow quantification in lab-on-a-chip systems and inline flow sensors for biological fluids. Aim: To study flow in highly scattering samples (1 to Approach: MC-Doppler uses unit vectors and ray tracing to model light propagation, with fully customizable scattering phase functions and flow fields. It was tested with various suspensions of differently sized polystyrene beads, at flow rates ranging from 0 to Results: Simulated and measured Doppler power spectra matched well for scattering coefficients up to Conclusions: MC-Doppler accurately simulates light propagation for through-transmission laser Doppler up to moderate scattering coefficients.

Indexed as

Laser-Doppler FlowmetryMonte Carlo MethodComputer SimulationHumansLightPhantoms, ImagingScattering, Radiationhuman milklaser Doppler flowmetrylight scatteringmonodisperse suspensionsMonte Carlo simulations

Identifiers

PMID40873853
PMCPMC12379725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.