ReviewCureus2025
Colorectal Cancer Risk and Protective Factors Among People of African Descent: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide, particularly affecting populations in low- and middle-income countries. Lower screening utilization among African descent has been linked to delayed diagnosis and early intervention. This review aims to identify the most common risk and protective factors of CRC among people of African descent. A comprehensive search was conducted on PubMed and Google Scholar databases from inception to the 21st of April 2025, and 5062 articles were synthesized. Of these, 30 articles were included for final qualitative analysis, data extraction, and meta-analysis. We included original peer-reviewed articles written in the English language that report CRC patients' possible risk or protective factors for CRC among adult patients of any gender and of African descent in any country around the world. Our review included 53,596 people of African descent across nine countries, and 8317 (16%) of them were diagnosed with CRC via colonoscopy and histology. The non-modifiable risk factors reported include: age > 55 years, family history of CRC, male gender, family history of malignancy, and genetic mutation, while the modifiable risk factors include: tobacco smoking, frequent consumption of alcohol, red/processed/roasted meat (suya), a fat diet, BMI > 30 kg/m²,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.