Evidence map›Paper›PMID 40873818›Full record

ArticleCureus2025

Relationship Between Postoperative Feeding Status and Salivary Bacterial Load Following Oral Surgical Procedures.

Teruyuki Niimi, Sakiko Soutome, Akira Imakiire, Hideto Imura, Masahito Hara, Kei-Ichiro Miura, Mitsunobu Otsuru, Tomohiro Yamada, Masahiro Umeda, Nagato Natsume

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Teruyuki NiimiDivision of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.
Sakiko SoutomeDepartment of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.
Akira ImakiireDepartment of Oral Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.
Hideto ImuraDepartment of Oral and Maxillofacial Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.
Masahito HaraDepartment of Oral and Maxillofacial Surgery, Nagasaki University, Nagasaki, JPN.
Kei-Ichiro MiuraDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, JPN.
Mitsunobu OtsuruDepartment of Oral and Maxillofacial Surgery, Kanagawa Dental University, Yokosuka, JPN.
Tomohiro YamadaDepartment of Oral and Maxillofacial Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.
Masahiro UmedaDivision of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.
Nagato NatsumeDivision of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOral and maxillofacial surgery involves clean-contaminated wounds exposed to saliva, increasing the risk of surgical site infections (SSIs). While systemic antibiotics are commonly used postoperatively, the effect of feeding status on salivary bacterial counts remains unclear.

methodsThis prospective observational study included 24 patients (greater than or equal to six years) undergoing oral surgery with postoperative enteral feeding. Salivary bacterial counts were measured preoperatively, during enteral feeding, liquid diet, and regular diet phases using real-time polymerase chain reaction targeting the 16S ribosomal ribonucleic acid gene. Statistical analysis was performed using paired t-tests.

resultsDuring enteral feeding, all patients received systemic antibiotics, and salivary bacterial counts remained comparable to preoperative levels (101%). In the liquid diet phase, bacterial counts decreased with ongoing antibiotics (88%) but increased without antibiotics (122%). During the regular diet phase, counts returned to baseline (98%).

conclusionSystemic antibiotics suppress salivary bacterial growth, while reduced oral intake may increase bacterial burden. Additional oral hygiene measures may be necessary during the transition period to prevent SSIs.

Indexed as

feeding statusoral surgical proceduressalivary bacterial countsurgical site infectionssystemic antibiotic administration

Identifiers

PMID40873818
PMCPMC12380502

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.