Evidence map›Paper›PMID 40873763›Full record

ArticleEuropean heart journal. Case reports2025

Successful implantation of an extravascular implantable cardioverter-defibrillator in a patient with moderate pectus excavatum: a case report.

Holden Eaton, Hesham Aggour, Julian O M Ormerod

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Holden EatonUniversity of Oxford Medical School, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK.ORCID https://orcid.org/0009-0005-9779-1017
Hesham AggourDepartment of Cardiovascular Medicine, University of Oxford, Wellington Square, Oxford OX1 2JD, UK.ORCID https://orcid.org/0000-0003-4825-4002
Julian O M OrmerodDepartment of Cardiovascular Medicine, University of Oxford, Wellington Square, Oxford OX1 2JD, UK.ORCID https://orcid.org/0000-0003-1612-8992

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Implantable cardioverter-defibrillators (ICDs) prevent sudden cardiac death due to ventricular arrhythmia. A novel extravascular ICD (EV-ICD) system provides improved functionality over previous transvenous (TV-ICD) and subcutaneous (S-ICD) alternatives, particularly in younger patients. This includes limited bradycardia pacing, anti-tachycardia pacing therapy, and lower energy defibrillation, all within a smaller device profile compared to the S-ICD. Due to the need for substernal lead placement, however, complex sternal anatomy is currently considered a relative contraindication to their use. Case summary: We present a 38-year-old male patient with pectus excavatum and a previous episode of ventricular fibrillation leading to out-of-hospital cardiac arrest. Initial implantation of a S-ICD was associated with repeated inappropriate shocks over 4 years, leading to multidisciplinary discussions with the patient regarding off-label use of an EV-ICD, as approved by Medtronic CRM. Explantation of the S-ICD and implantation of the EV-ICD were successful, with minimal technical changes required compared to standard surgical technique in normal sternal anatomy. At 6-month follow-up, there were no complications or inappropriate shocks. Discussion: The EV-ICD may be considered in patients with pectus excavatum, making this novel device available to a larger proportion of patients. Aside from careful consideration of instrument positioning during the procedure, this can be done with minimal changes to the standard surgical protocol.

Indexed as

Case reportEV-ICDICDPectus excavatumVentricular fibrillation

Identifiers

PMID40873763
PMCPMC12378624

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.