ArticleInfection and drug resistance2025
Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study.
Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Evolving Triad of Carbapenem Resistance: Emergence of Dominant CRPA, Persistent CRAB, and Rebounding CRKP in a Chinese Regional Hospital (2020-2024).Infection and drug resistance · 2026Article
- Epidemiological characteristics and antimicrobial resistance of pathogens isolated from blood cultures in southern Jiangxi, China, 2020-2024.Frontiers in cellular and infection microbiology · 2025Article
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3 authors.
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Abstract
Purpose: This study aimed to characterize the epidemiological patterns and antimicrobial resistance profiles of bloodstream infections (BSIs) in a cardiovascular specialty hospital and to identify region-specific pathogen distributions, resistance risks, and clinical implications for optimizing empirical therapy and infection control strategies. Patients and Methods: A retrospective analysis (2018-2024) evaluated 1,055 non-duplicate BSI isolates from 37,576 blood cultures at the Fuwai Central China Cardiovascular Hospital. Researchers investigated both bacterial classification and associated drug resistance through comprehensive analysis. Results: The study revealed that a total of 1,055 bacterial strains were isolated from blood cultures, with Gram-negative bacteria accounting for 31.5% (332 strains), Gram-positive bacteria for 62.7% (662 strains), and fungi for 5.8% (61 strains). The most frequently isolated pathogens were Conclusion: Blood culture isolates in our hospital demonstrated a predominance of Gram-positive organisms, with high detection rates of MRSA, MRCNS, and carbapenem-resistant Gram-negative bacilli. Continuous antimicrobial resistance surveillance of bloodstream isolates should be maintained in clinical practice to provide evidence-based data for rational antibiotic use and mitigate the emergence of resistant pathogens.
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