ArticleFrontiers in microbiology2025
Comparison of extracellular vesicles carrying bacterial DNA in urine and serum from a Korean population.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Gut microbiota-derived extracellular vesicles: bridging microbial-host crosstalk in metabolic disorders.Cell communication and signaling : CCS · 2026Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Bacteria-derived extracellular vesicles (BEVs) are emerging as key biomarkers of host-microbiota interactions. However, little is known about how BEV profiles differ across different biofluids or how these differences relate to clinical phenotypes. We aimed to examine the BEV distribution and site-specific and shared associations with host phenotypes, and evaluated the clinical relevance of microbial distance between sampling sites. Methods: We profiled BEVs using 16S rRNA sequencing of urine and serum samples from middle-aged and older Koreans ( Results: Urine BEVs exhibited higher alpha diversity than the serum BEVs, as well as stronger associations with dietary nutrient intake, particularly sugar, and with anthropometric measures such as waist circumference. The correlations between the urine and serum BEV compositions were generally low, emphasizing their distinct microbial profiles. Notably, individuals with shorter urine-serum BEV composition distances had higher waist-to-hip and sugar-to-fat ratios. Discussion: This study provides a comprehensive comparison of urinary and serum BEVs, revealing the differences in microbial composition and associations with host phenotypes. In particular, urine BEVs showed stronger associations with dietary and metabolic factors, underscoring their potential utility as non-invasive biomarkers for metabolic health.
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