Evidence map›Paper›PMID 40873697›Full record

ArticleBiomedical image registration, ... proceedings. WBIR (Workshop : 2006- )2024

Registration by Regression (RbR): a framework for interpretable and flexible atlas registration.

Karthik Gopinath, Xiaoling Hu, Malte Hoffmann, Oula Puonti, Juan Eugenio Iglesias

Abstract read
In one paragraph

Article in Biomedical image registration, ... proceedings. WBIR (Workshop : 2006- ), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Fast segmentation with the NextBrain histological atlas.bioRxiv : the preprint server for biology · 2025
    Article
  2. MultiMorph: On-demand Atlas Construction.Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition · 2025
    Article
  3. Hierarchical uncertainty estimation for learning-based registration in neuroimaging.... International Conference on Learning Representations · 2025
    Article
  4. Article
  5. Fast segmentation with the NextBrain histological atlas.Imaging neuroscience (Cambridge, Mass.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karthik GopinathMassachusetts General Hospital and Harvard Medical School.
Xiaoling HuMassachusetts General Hospital and Harvard Medical School.
Malte HoffmannMassachusetts General Hospital and Harvard Medical School.
Oula PuontiMassachusetts General Hospital and Harvard Medical School.
Juan Eugenio IglesiasMassachusetts General Hospital and Harvard Medical School.

Funding

Functionally guided adult whole brain cell atlas in human and NHPUM1MH130981 · NIMH · ALLEN INSTITUTE · PI Ed Lein, Hongkui Zeng · 2022 to 2026
$91.9M
Acquisition-independent machine learning for morphometric analysis of underrepresented aging populations with clinical and low-field brain MRIRF1AG080371 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Juan Eugenio Iglesias Gonzalez · 2023 to 2026
$4.0M
Diagnosing the undiagnosable: studies of Alzheimer disease mimics and confounders via "neuropathometry" of dissection photos with 3D scanningR01AG070988 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI IGLESIAS GONZALEZ, JUAN EUGENIO · 2021 to 2025
$2.7M
Open-source software for multi-scale mapping of the human brainRF1MH123195 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE, IGLESIAS GONZALEZ, JUAN EUGENIO · 2020 to 2020
$2.0M
Fast motion-robust fetal neuroimaging with MRIR00HD101553 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI HOFFMANN, MALTE · 2023 to 2025
$743k
NIA NIH HHS R01 AG070988NIA NIH HHS RF1 AG080371NICHD NIH HHS R00 HD101553NIMH NIH HHS RF1 MH123195NIMH NIH HHS UM1 MH130981
6 · The paper itself

Abstract

In human neuroimaging studies, atlas registration enables mapping MRI scans to a common coordinate frame, which is necessary to aggregate data from multiple subjects. Machine learning registration methods have achieved excellent speed and accuracy but lack interpretability and flexibility at test time (since their deformation model is fixed). More recently, keypoint-based methods have been proposed to tackle these issues, but their accuracy is still subpar, particularly when fitting nonlinear transforms. Here we propose Registration by Regression (RbR), a novel atlas registration framework that: is highly robust and flexible; can be trained with cheaply obtained data; and operates on a single channel, such that it can also be used as pretraining for other tasks. RbR predicts the (

Identifiers

PMID40873697
PMCPMC12380105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.