Evidence map›Paper›PMID 40873688›Full record

ArticleSIAM journal on imaging sciences2023

A Common Lines Approach for Ab Initio Modeling of Molecules with Tetrahedral and Octahedral Symmetry.

Adi Shasha Geva, Yoel Shkolnisky

Abstract read
In one paragraph

Article in SIAM journal on imaging sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adi Shasha GevaDepartment of Applied Mathematics, School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel.
Yoel ShkolniskyDepartment of Applied Mathematics, School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel.

Funding

Reconstruction of heterogeneous and small macromolecules by cyro-EMR01GM136780 · NIGMS · PRINCETON UNIVERSITY · PI SINGER, AMIT · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM136780
6 · The paper itself

Abstract

A main task in cryo-electron microscopy single particle reconstruction is to find a three-dimensional model of a molecule given a set of its randomly oriented and positioned projection-images. In this work, we propose an algorithm for ab initio reconstruction for molecules with tetrahedral or octahedral symmetry. The algorithm exploits the multiple common lines between each pair of projection-images as well as self common lines within each image, and integrates the information from all images at once. The applicability of the proposed algorithm is demonstrated using simulated and experimental cryo-electron microscopy data.

Indexed as

92-08ab initio reconstructionangular reconstitutioncryo-electron microscopysingle particle reconstructionsymmetrysynchronization

Identifiers

PMID40873688
PMCPMC12380372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.