Evidence map›Paper›PMID 40873674›Full record

SynthesisFrontiers in psychiatry2025

How many people die by suicide each year? Not 727,000: a systematic review and meta-analysis of suicide underreporting across 71 countries over 122 years.

Nicola Meda, Ludovica Angelozzi, Matteo Poletto, Angelo Patane', Josephine Zammarrelli, Irene Slongo, Fabio Sambataro, Diego De Leo

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicola MedaDepartment of Neuroscience, University of Padova, Padova, Italy.
Ludovica AngelozziDepartment of Neuroscience, University of Padova, Padova, Italy.
Matteo PolettoDepartment of Neuroscience, University of Padova, Padova, Italy.
Angelo Patane'Department of Neuroscience, University of Padova, Padova, Italy.
Josephine ZammarrelliDe Leo Fund, Padova, Italy.
Irene SlongoIndependent Researcher, Padova, Italy.
Fabio SambataroDepartment of Neuroscience, University of Padova, Padova, Italy.
Diego De LeoDe Leo Fund, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Suicide underreporting undermines accurate public health assessments and resource allocation for suicide prevention. This study aims at synthesizing evidence on suicide underreporting and to estimate a global underreporting rate. Methods: We conducted a PRISMA-compliant systematic review on suicide underreporting, following a pre-registered protocol. A meta-analytical synthesis was also conducted. Quantitative data from individual studies was extracted to provide an overall global estimate of suicide underreporting (42 studies covering 71 countries out of the initial 770 unique studies, spanning 1900-2021). Most studies used retrospective institutional datasets to estimate underreporting through reclassification of undetermined deaths or comparisons across databases. Demographic and geographic disparities were also examined. Results: The 42 studies selected provided some quantitative data on suicide underreporting for general or specific populations. 14 of these studies provided data to be meta-analyzed. The global suicide underreporting rate was estimated to be 17.9% (95% CI: 10.9-28.1%) with large differences between countries with high and low/very low data quality. In this scenario, the last WHO estimates of suicide deaths - corrected for underreporting - would be more than one million (1,000,638; 95% CI: 859,511-1,293,006) and not 727,000 suicides per year. Underreporting was higher in low- and middle-income countries (LMICs) with incomplete death registration systems, such as India and China (34.9%; 95% CI 20.3-53%), while high-income countries exhibited lower rates (11.5%; 95% CI 6.6-19.3%). Contributing factors included stigma, religiosity, limited forensic resources, and inconsistent use of International Classification of Diseases (ICD) codes. Gender and age disparities were notable; Female suicides and those among younger or older individuals were more likely to be misclassified. Discussion: Addressing suicide underreporting requires improving death registration systems globally, particularly in LMICs. Standardizing ICD usage, improving forensic capacity, and reducing stigma are critical steps to ensure accurate data. Heterogeneity, geographical disparities, temporal biases, and invariance of suicide underreporting for countries with low-quality data demand further corroboration of these findings. Systematic Review Registration: https://osf.io/9j8dg.

Indexed as

global burdenglobal health estimatesmisclassificationsuicideunder-reporting

Identifiers

PMID40873674
PMCPMC12378953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.