Evidence map›Paper›PMID 40873638›Full record

ArticleExploration (Beijing, China)2025

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD-Bronchiectasis Association: A Prospective Cohort Study.

Zhen-Feng He, Xiao-Xian Zhang, Cui-Xia Pan, Xin-Zhu Yi, Yan Huang, Chun-Lan Chen, Shan-Shan Zha, Lai-Jian Cen, Han-Qin Cai, Lei Yang and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Exploration (Beijing, China), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Microbial dysbiosis and inferred functional profiling reveals the potential role ofFrontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Microbiome and its role in bronchiectasis.Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Zhen-Feng HeDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Xiao-Xian ZhangDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Cui-Xia PanDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Xin-Zhu YiInstitute of Ecological Sciences School of Life Sciences South China Normal University Guangzhou China.
Yan HuangDepartment of Geriatrics National Key Clinical Specialty Guangzhou First People's Hospital South China University of Technology Guangzhou China.
Chun-Lan ChenDepartment of Respiratory and Critical Care Medicine Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou China.
Shan-Shan ZhaDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Lai-Jian CenDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Han-Qin CaiInstitute of Ecological Sciences School of Life Sciences South China Normal University Guangzhou China.
Lei YangInstitute of Ecological Sciences School of Life Sciences South China Normal University Guangzhou China.
Jia-Qi GaoInstitute of Ecological Sciences School of Life Sciences South China Normal University Guangzhou China.
Hui-Min LiDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Zhen-Hong LinDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Sheng-Zhu LinDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Zhang WangInstitute of Ecological Sciences School of Life Sciences South China Normal University Guangzhou China.
Nan-Shan ZhongDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.
Wei-Jie GuanDepartment of Allergy and Clinical Immunology Department of Respiratory and Critical Care Medicine State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory Disease National Center for Respiratory Medicine Guangzhou Institute of Respiratory Health First Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong P.R. China.ORCID https://orcid.org/0000-0001-5463-391X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiectasis frequently co-exists with chronic obstructive pulmonary disease (COPD-bronchiectasis association [CBA]). We compared the microbiota and metabolome of bronchiectasis with (BO) and without airflow obstruction (BNO), COPD, and CBA. We determined how microbiota compositions correlated with clinical characteristics and exacerbations of CBA. We prospectively recruited outpatients with BNO (

Indexed as

BronchiectasisCOPDCOPD‐Bronchiectasis associationexacerbationmetabolomemicrobiota

Identifiers

PMID40873638
PMCPMC12380057

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.