ReviewToxicological research2025
Pre and postnatal exposure to glyphosate-based herbicides and potential neurodevelopmental outcomes: a systematic review of animal and epidemiological studies.
Review in Toxicological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pesticide exposure and the risk of arterial hypertension and obesity in farm workers: a systematic review of literature.BMC cardiovascular disorders · 2026Pooled it
- Nanoemulsion of Apium graveolens essential oil as a natural pre-emergent herbicide.Scientific reports · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence indicates potential adverse effects on infant neurodevelopment from exposure to glyphosate during prenatal and postnatal periods. This systematic review examines the scientific literature to explore links between prenatal/postnatal glyphosate exposure and neurodevelopmental abnormalities in humans and non-humans. Twenty-five original articles were reviewed, focusing on the following descriptors: glyphosate-based herbicides, pre and postnatal exposure, and neurodevelopmental outcomes. Risk of bias assessment was conducted to quality of studies. Experimental studies commonly used tests such as open field and novel object recognition, while epidemiological studies relied on medical records for diagnoses of conditions like depression and autism-like behavior. Surprisingly, only one experimental study directly measured glyphosate levels, and one of the epidemiological studies included a biomarker measure. In rodents, GLY exposure was associated to impaired cognition, motor function, memory, as well as ASD and anxiety-like behavior. In fish models, impairment of swimming activity was predominant. Overall, findings suggest possible associations between glyphosate exposure and neurodevelopmental deficits, emphasizing the need for further research to comprehend the extent of glyphosate's impact on developmental functioning. Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s43188-025-00294-z.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.