Evidence map›Paper›PMID 40873294›Full record

ArticleEuropean stroke journal2025

Conventional versus advanced imaging selection for endovascular treatment of basilar artery occlusion strokes.

Huanwen Chen, Marco Colasurdo, Hidetoshi Matsukawa, Conor Cunningham, Ilko Maier, Sami Al Kasab, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai and 32 more

Abstract read
In one paragraph

Article in European stroke journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

Huanwen ChenNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-2455-748X
Marco ColasurdoOregon Health & Science University Hospital, Portland, OR, USA.
Hidetoshi MatsukawaMedical University of South Carolina, Charleston, SC, USA.
Conor CunninghamMedical University of South Carolina, Charleston, SC, USA.
Ilko MaierUniversitätsmedizin Göttingen, Göttingen, Germany.ORCID 0000-0001-6988-8878
Sami Al KasabMedical University of South Carolina, Charleston, SC, USA.
Pascal JabbourThomas Jefferson University, Philadelphia, PA, USA.ORCID 0000-0002-8965-2413
Joon-Tae KimChonnam National University Hospital, Gwangju, Republic of Korea.
Stacey Quintero WolfeWake Forest Baptist Health, Lexington, NC, USA.
Ansaar RaiWest Virginia University, Morgantown, WV, USA.
Robert M StarkeUniversity of Miami Health System, Miami, FL, USA.
Marios-Nikos PsychogiosUniversitätsspital Basel, Basel, Switzerland.
Edgar A SamaniegoUniversity of Iowa, Iowa City, IA, USA.ORCID 0000-0003-2764-2268
Nitin GoyalUniversity of Tennessee Health Science Center, Semmes Murphey Foundation, Memphis, TN, USA.
Shinichi YoshimuraHyogo College of Medicine, Hyogo, Japan.
Hugo CuellarLSU Health Shreveport, Shreveport, LA, USA.
Jonathan A GrossbergEmory University, Atlanta, GA, USA.
Ali AlawiehEmory University, Atlanta, GA, USA.
Ali AlarajUniversity of Chicago at Illinois, Chicago, IL, USA.
Mohamad EzzeldinUniversity of Houston, HCA Houston Healthcare Kingwood, Kingwood, TX, USA.
Daniele G RomanoAou S. Giovanni di Dio e Ruggi d'Aragona, Salerno, SA, Italy.
Omar TanweerBaylor College of Medicine, Houston, TX, USA.
Justin MascitelliUniversity of Texas Health Science Center at San Antonio, San Antonia, TX, USA.
Isabel FragataNOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal.
Adam PolifkaUniversity of Florida, Gainesville, FL, USA.
Fazeel SiddiquiUniversity of Michigan Health West, Wyoming, MI, USA.
Joshua OsbunWashington University in St. Louis, St. Louis, MO, USA.
Roberto CrosaMédica Uruguaya, Montevideo, Uruguay.
Charles MatoukYale University, New Haven, CT, USA.
Min S ParkUniversity of Virginia, Charlottesville, VA, USA.
Michael R LevittUniversity of Washington, Seattle, WA, USA.
Waleed BrinjikjiMayo Clinic in Minnesota, Rochester, MN, USA.
Mark MossWashington Regional Medical Center, Fayetteville, AR, USA.
Travis DumontUniversity of Arizona, Tucson, AZ, USA.
Ergun DagliogluHealth Science University, Ankara Bilkent City Hospital, Ankara, Turkey.
Richard WilliamsonAlleghany Hospital, Pittsburgh, PA, USA.
Pedro NaviaHospital Universitario La Paz, Madrid, Spain.
Reade De LeacyMount Sinai Health System, New York, NY, USA.
Shakeel ChowdhryNorth Shore University Health System, Evanston, IL, USA.
David J AltschulMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Alejandro M SpiottaMedical University of South Carolina, Charleston, SC, USA.
Peter KanUniversity of Texas Medical Branch at Galveston, Galveston, TX, USA.

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
Miami Clinical and Translational Science InstituteUL1TR000460 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SACCO, RALPH L. · 2012 to 2016
$16.9M
Miami Clinical and Translational Science InstituteUM1TR004556 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Olveen Carrasquillo, ERIN N KOBETZ · 2023 to 2026
$16.0M
Institutional Career Development CoreKL2TR002737 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA, SCOTT, GWENDOLYN BARBARA · 2018 to 2022
$3.6M
Endothelial cell dysfunction in cerebral aneurysm pathogenesisR01NS111119 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI STARKE, ROBERT MICHAEL · 2020 to 2024
$2.4M
Development of a Wireless Endovascular Nerve Stimulator for Treatment of Refractory Neuropathic PainU18EB029353 · NIBIB · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAN, PETER TZE MAN, ROBINSON, JACOB T. · 2019 to 2019
$2.3M
Electroencephalographic signatures of dysfunctional cerebrovascular autoregulation as biomarkers of brain injury in aneurysmal subarachnoid hemorrhage (SAH)R21NS128641 · NINDS · YALE UNIVERSITY · PI KIM, JENNIFER A, MATOUK, CHARLES · 2023 to 2024
$461k
NCATS NIH HHS KL2 TR002737NCATS NIH HHS UL1 TR000460NCATS NIH HHS UL1 TR002736NCATS NIH HHS UM1 TR004556NIBIB NIH HHS U18 EB029353NINDS NIH HHS R01 NS111119NINDS NIH HHS R21 NS128641
6 · The paper itself

Abstract

introductionEndovascular thrombectomy (EVT) is an effective treatment for basilar artery occlusion (BAO) stroke in select patients. While there is a growing body of literature suggesting that advanced imaging modalities such as computed tomography perfusion (CTP) and magnetic resonance (MR) may not be necessary for selecting anterior circulation large vessel occlusion stroke patients for EVT, whether advanced imaging may be superior to conventional imaging (non-contrast CT and CT angiography) in identifying good treatment candidates among BAO patients is less clear. PATIENTS AND

methodsThis was a multicenter retrospective cohort study of BAO EVT patients treated from 2013 to 2022 in the Stroke Thrombectomy and Aneurysm Registry. Patients selected for EVT by advanced imaging (CTP or MR) were matched with those selected by conventional imaging using propensity score matching (PSM) accounting for possible confounders. Primary outcome was functional independence at 90 days. Other outcomes include bedridden state or death at 90-days and symptomatic intracranial hemorrhage (sICH).

results268 patients were included. 150 patients were selected for BAO EVT by conventional imaging, 86 by CTP, and 32 by MR. Patients selected by advanced imaging were significantly older than those selected by conventional imaging (median age 71 vs 64 years,

conclusionsSelecting patients for basilar EVT using conventional versus advanced imaging did not result in different clinical outcomes, regardless of treatment time windows. Conventional imaging appears sufficient as a first-line tool for selecting basilar EVT patients in routine clinical practice.

Indexed as

ASPECTBasilarcomputed tomographyhemorrhageimagingmagnetic resonanceperfusionstrokethrombectomytime window

Identifiers

PMID40873294
PMCPMC12394210

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