Evidence map›Paper›PMID 40873280›Full record

ArticleCurrent medical imaging2025

Preliminary Study on the Evaluation Value of Extracellular Volume Fraction in the Pathological Grading of Lung Invasive Adenocarcinoma

Bin Nan, Yukun Pan, Yinghui Ge, Minghua Sun, Jin Cai, Xiaojing Kan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bin NanDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Henan Provincial Key Laboratory of Cardiology Medical Imaging, Zhengzhou, Henan 450003, China.ORCID 0009-0001-7797-6349
Yukun PanDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Henan Provincial Key Laboratory of Cardiology Medical Imaging, Zhengzhou, Henan 450003, China.
Yinghui GeDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Henan Provincial Key Laboratory of Cardiology Medical Imaging, Zhengzhou, Henan 450003, China.
Minghua SunDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Henan Provincial Key Laboratory of Cardiology Medical Imaging, Zhengzhou, Henan 450003, China.
Jin CaiDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Henan Provincial Key Laboratory of Cardiology Medical Imaging, Zhengzhou, Henan 450003, China.
Xiaojing KanDepartment of Radiology, Fuwai Central China Cardiovascular Hospital, Henan Provincial Key Laboratory of Cardiology Medical Imaging, Zhengzhou, Henan 450003, China.ORCID 0000-0003-2197-1714

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to evaluate the diagnostic value of extracellular volume fraction (ECV) and spectral CT parameters in assessing the pathological grading of lung invasive adenocarcinoma (IAC) presenting as solid or subsolid nodules.

methodsA retrospective collection of patients who were pathologically confirmed as IAC with solid or subsolid pulmonary nodules at our hospital from March 2023 to November 2024 was conducted. Relevant data were recorded, and the patients were divided into two groups: intermediate/high differentiation and low differentiation. The parameters including arterial phase iodine concentration (IC

resultsA total of 61 patients were included, comprising 40 in the intermediate to high differentiation group and 21 in the low differentiation group. The intermediate/high differentiation group had higher values of ECV DISCUSSION: ECVV outperforms other spectral parameters in differentiating IAC grades, reflecting changes in the tumor microenvironment. Combining ECV

conclusionExtracellular volume fraction can provide more information for the pathological grading assessment of invasive adenocarcinoma of the lung. Compared to other spectral parameters, ECV

Indexed as

Adenocarcinoma of LungLung NeoplasmsTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedNeoplasm GradingNeoplasm InvasivenessRetrospective StudiesROC CurveAdenocarcinomaDiagnosisDifferential.Dual-energy CT imagingLung neoplasmsTomographyX-ray computed

Identifiers

PMID40873280
PMCPMC13223411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.