Evidence map›Paper›PMID 40873239›Full record

ArticleJournal of human nutrition and dietetics : the official journal of the British Dietetic Association2025

Chronic Diseases Related to Diet and/or Nutrition in Patients With an Ileostomy - A Scoping Review.

Tjun Wei Leow, Georgia Herbert, Alexandra Mitchell, Rachel Perry, David J Humes, Gabrielle Thorpe, Scott Clifford, Charlotte Atkinson, Clare England

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tjun Wei LeowDivision of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID https://orcid.org/0000-0001-8288-2139
Georgia HerbertNIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.
Alexandra MitchellSchool of Healthcare Sciences, Cardiff University, Cardiff, UK.
Rachel PerryNIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.
David J HumesGastrointestinal Surgery, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, School of Medicine, Queen's Medical Centre, Nottingham, UK.
Gabrielle ThorpeSchool of Health Sciences, University of East Anglia, Norwich, UK.
Scott CliffordNIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.
Charlotte AtkinsonNIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-6684-4431
Clare EnglandNIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0003-0685-0690

Funding

This study is funded by the National Institute for Health Research (NIHR) Bristol Biomedical Research Centre (BRC) Nutrition Theme, based at University Hospitals Bristol NHS Foundation Trust and the University of Bristol. This study is also supported by the National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West). The views expressed in this article are those of the authors and not necessarily those of the NIHR or the Department of Health and Social.
6 · The paper itself

Abstract

aimIleostomy formation alters bowel function and is associated with changes that could lead to the development of chronic diseases. The literature on these diseases has not previously been summarised and specific guidelines on their management are absent. This scoping review aimed to explore the extent and type of literature examining such diseases.

methodsMEDLINE, Embase, CINAHL, AMED, and Web of Science were searched from database inception to 28 April 2025. Studies on chronic diseases (kidney, bone, metabolic disease, and anaemia) related to diet and/or nutrition in adults with any type of ileostomy were included. Patients on parenteral/enteral nutrition were excluded. Screening and data extraction were conducted by pairs of independent reviewers. Results were reported according to PRISMA-ScR guidelines.

resultsTwenty independent studies (21 full texts) met the inclusion criteria, with sample sizes ranging from 14 to 19,889. Eight full texts reported on kidney disease, five on anaemia/B12 deficiency, four on bone and metabolic disease respectively. The incidence of CKD ranged from 0% to 63.8%, osteopenia from 29.4% to 48.0%, osteoporosis from 5% to 12%, and metabolic disease from 11.8% to 28%. Anaemia incidence was found to be 7.2% and B12 deficiency ranged from no association to 31.8%.

conclusionCurrent evidence on the risk of chronic diseases associated with ileostomy formation is weakened by studies of small sample size and high heterogeneity of population, methodologies and outcomes. Further studies need to stratify rates by ileostomy indication, length of time with an ileostomy, and effect of ileostomy reversal.

Indexed as

DietIleostomyAdultAnemiaChronic DiseaseFemaleHumansMetabolic DiseasesNutritional StatusRenal Insufficiency, Chronicchronic diseasedietileostomynutritionscoping review

Identifiers

PMID40873239
PMCPMC12391853

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.