ReviewCNS & neurological disorders drug targets2026
Decoding the Gut-Brain Axis in Alzheimer's Disease: Emerging Perspectives.
Review in CNS & neurological disorders drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Gastrointestinal dysfunction after brain injury: Mechanisms and the role of the brain-gut axis.World journal of gastroenterology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is a leading source of dementia, evidenced by cognitive debility, tau neurofibrillary tangles, and amyloid-β plaques. Recent studies emphasize the gut-brain axis as a vital element in the pathogenesis of Alzheimer's disease, involving microbial, neuronal, immunological, and hormonal mechanisms. The composition of gut microbiota dysbiosis is determined by growth in intestinal barrier permeability and activation of immune cells, which causes impaired function of the blood-brain barrier that stimulates neural injury, neuronal loss, neuroinflammation, and eventually AD. Various studies have reported that the gut microbiota plays a crucial role in brain function and changes in individual behavior, as well as in bacterial amyloid formation. Growing experimental and clinical data specify the conspicuous role of intestinal dysbiosis and microbiota- host interactions in AD. The importance of this paper is the focus on the potential association of AD and gut microbiota and also a discussion of the therapeutic modalities of inhibiting gut dysbiosis.
Indexed as
Identifiers
40873226What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.