Evidence map›Paper›PMID 40873224›Full record

ReviewMini reviews in medicinal chemistry2025

Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review.

Prabhjot Kaur, Divya Utreja, Shivali Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Prabhjot KaurDepartment of Chemistry, Punjab Agricultural University, Ludhiana, Punjab, 141004, India.
Divya UtrejaDepartment of Chemistry, Punjab Agricultural University, Ludhiana, Punjab, 141004, India.
Shivali SharmaDepartment of Chemistry, Punjab Agricultural University, Ludhiana, Punjab, 141004, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing resistance of causative agents to current treatments has made infectious disease management more challenging. Heterocyclic compounds have garnered considerable attention due to their numerous significant medical and biological applications. Research interest in heterocyclic compounds is rapidly increasing due to extensive synthetic studies and their functional utility. Phenothiazine (PTZ), an organic thiazine compound, has a broad range of biological activities, including antimicrobial, antimalarial, antipsychotic, anti-inflammatory, and antiemetic effects. Additionally, modifications to the phenothiazine structure have enhanced its efficacy, making it a potential candidate for addressing drug-resistant infections. This review examines recent synthesis methods, including catalytic and microwave-assisted techniques, which have expanded the applications of phenothiazine derivatives. The article also discusses structure-activity relationships, which help optimize the pharmacological properties of these compounds for future therapeutic use.

Indexed as

Anti-Infective AgentsPhenothiazinesAnimalsAnti-Inflammatory AgentsAntipsychotic AgentsHumansStructure-Activity RelationshipAnti-Infective AgentsAnti-Inflammatory AgentsAntipsychotic AgentsphenothiazinePhenothiazinesantibacterialantimicrobialanti-parkinsonHeterocyclic compoundsphenothiazinetherapeutic use.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.