Observational studyAnaesthesia2025
Effects of anaesthesia and surgery on sleep-wake timing and subjective sleep quality in children: an observational study.
Observational study in Anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- The implications of circadian rhythms for anaesthesia.BJA education · 2026Review
- Alterations in the DTI-ALPS index and choroid plexus volume are associated with symptom severity in children with tic disorders.BMC neurology · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSurgery and anaesthesia can cause disruption of the circadian timing system and diurnal sleep-wake rhythm. However, it remains unknown how sleep-wake rhythm in children is affected by anaesthesia and surgery, and if anaesthesia without a surgical procedure disturbs sleep-wake cycles.
methodsWe recruited children aged 1-11 y undergoing anaesthesia for an elective surgical procedure or magnetic resonance imaging. The Children's Chronotype Questionnaire, Children's Sleep Habits Questionnaire and a daily sleep diary from three days before until seven days after anaesthesia were used to assess sleep-wake rhythm and sleep quality.
resultsIn total, 117 patients (median (IQR [range]) age 4 (2-6 [1-11]) y, 56 (47.9%) female) were included. The midpoint of sleep did not change on the night after anaesthesia when compared with three nights before (estimated median time difference 8 min, 95%CI -15-1, p = 0.12, n = 114). Median (IQR [range]) midpoint of sleep at baseline was 01.42 (01.22-02.19 [00.10-03.15]) for the surgical group and 01.22 (01.03-02.07 [00.15-04.02]) for the magnetic resonance imaging group. The midpoint of sleep did not shift on the night after anaesthesia for either group (surgical group: 01.37 (01.07-02.15 [23.00-03.12]), estimated median time difference -15 min, 95%CI -27-0, p = 0.07, n = 58; magnetic resonance imaging group: 01.30 (01.07-02.07 [23.45-05.00]), estimated median time difference 0 min, 95%CI -9-9, p = 0.90, n = 56), and there was no between-group difference (estimated median time difference: -15 min, 95%CI -30-0 min, p = 0.07). Subjective sleep quality was unaffected. DISCUSSION: We found no disruption of sleep-wake rhythm in children after anaesthesia and surgery. Further research is needed to see whether more invasive procedures and accompanying anaesthesia pose a risk of disrupting sleep-wake rhythms in children.
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