Evidence map›Paper›PMID 40872925›Full record

ArticleVaccines2025

Awareness, Preference, and Acceptance of HPV Vaccine and Related Influencing Factors Among Guardians of Adolescent Girls in China: A Health Belief Model-Based Cross-Sectional Study.

Shuhan Zheng, Xuan Deng, Li Li, Feng Luo, Hanqing He, Ying Wang, Xiaoping Xu, Shenyu Wang, Yingping Chen

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuhan ZhengSchool of Public Health, Hangzhou Medical College, Hangzhou 310053, China.ORCID 0009-0009-0846-5674
Xuan DengDepartment of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.ORCID 0000-0002-7299-6527
Li LiDepartment of Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 102206, China.ORCID 0000-0001-5237-3210
Feng LuoSchool of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Hanqing HeDepartment of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.ORCID 0000-0003-0863-5177
Ying WangDepartment of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Xiaoping XuDepartment of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Shenyu WangDepartment of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.ORCID 0000-0002-3328-3671
Yingping ChenDepartment of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.

Funding

Xuan Deng Zhejiang Provincial Medical Science and Technology Program Project (2022KY714, 2023KY629)Yingping Chen Scientific Research Project of Zhejiang Preventive Medicine Association (2025-B-06)Yingping Chen Zhejiang Provincial Science and Technology Program for Disease Prevention and Control (2025JK179)
6 · The paper itself

Abstract

backgroundCervical cancer poses a threat to the health of women globally. Adolescent girls are the primary target population for HPV vaccination, and guardians' attitude towards the HPV vaccine plays a significant role in determining the vaccination status among adolescent girls.

objectivesThis study aimed to explore the factors influencing guardians' HPV vaccine acceptance for their girls and provide clues for the development of health intervention strategies.

methodsCombining the health belief model as a theoretical framework, a questionnaire-based survey was conducted. A total of 2157 adolescent girls and their guardians were recruited. The multivariable logistic model was applied to explore associated factors.

resultsThe guardians had a high HPV vaccine acceptance rate (86.7%) for their girls, and they demonstrated a relatively good level of awareness regarding HPV and HPV vaccines. Factors influencing guardians' HPV vaccine acceptance for girls included guardians' education background (OR = 0.57, 95%CI = 0.37-0.87), family income (OR = 1.94, 95%CI = 1.14-3.32), risk of HPV infection (OR = 3.15, 95%CI = 1.40-7.10) or importance of the HPV vaccine for their girls (OR = 6.70, 95%CI = 1.61-27.83), vaccination status surrounding them (OR = 2.03, 95%CI = 1.41-2.92), awareness of negative information about HPV vaccines (OR = 0.59, 95%CI = 0.43-0.82), and recommendations from medical staff (OR = 2.32, 95%CI = 1.65-3.25). Also, guardians preferred to get digital information on vaccines via government or CDC platforms, WeChat platforms, and medical knowledge platforms.

conclusionsThough HPV vaccine willingness was high among Chinese guardians, they preferred to vaccinate their daughters at the age of 17-18 years, later than WHO's recommended optimal age period (9-14 years old), coupled with safety concerns. Future work should be conducted based on these findings to explore digital intervention effects on girls' vaccination compliance.

Indexed as

acceptanceadolescent girlsguardiansHBMHPV vaccine

Identifiers

PMID40872925
PMCPMC12390454

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.