Evidence map›Paper›PMID 40872858›Full record

ReviewViruses2025

The Role of Myxoma Virus Immune Modulators and Host Range Factors in Pathogenesis and Species Leaping.

Junior A Enow, Ana M Lopes, Joana Abrantes, Pedro J Esteves, Masmudur M Rahman

Abstract readReview
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junior A EnowBiodesign Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0002-4631-6989
Ana M LopesUMIB-Unit for Multidisciplinary Research in Biomedicine, ICBAS-School of Medicine and Biomedical Sciences, University of Porto, 4050-313 Porto, Portugal.
Joana AbrantesCIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Campus de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.ORCID 0000-0002-8391-7134
Pedro J EstevesCIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Campus de Vairão, Universidade do Porto, 4485-661 Vairão, Portugal.ORCID 0000-0002-6055-8298
Masmudur M RahmanBiodesign Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0002-7177-819X

Funding

Studies in Poxvirus Host Range Genes and TropismR01AI080607 · NIAID · UNIVERSITY OF FLORIDA · PI RAHMAN, MASMUDUR MOHAMMED · 2009 to 2025
$5.6M
Viral inhibition of cell death in host immune responsesR01AI148302 · NIAID · DUKE UNIVERSITY · PI MIAO, EDWARD A · 2020 to 2024
$3.0M
Unravelling the mechanisms of virus host species jumpR21AI190589 · NIAID · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Masmudur Mohammed Rahman · 2025 to 2026
$425k
Arizona Biomedical Research (ABRC) Investigator Award RFGA2022-010-22National Institute of Health R01AI080607, R21AI190589, R01AI148302 subaward A033649NIAID NIH HHS R01 AI080607NIAID NIH HHS R01 AI148302NIAID NIH HHS R21 AI190589
6 · The paper itself

Abstract

Myxoma virus (MYXV) is a leporipoxvirus that causes lethal disease in Leporids. Hares and rabbits belong to the Leporidae family and are believed to have had a common ancestor 12 million years ago. After seventy years of contact with European hares without causing mortalities or disease manifestation, a recombinant MYXV infected Iberian hares (

Indexed as

Host SpecificityImmunologic FactorsMyxoma virusPoxviridae InfectionsAnimalsGenome, ViralHaresHost-Pathogen InteractionsRabbitsVirulenceImmunologic Factorshost rangeimmune modulatorsleporipoxvirusmyxoma viruspoxvirusspecies leaping

Identifiers

PMID40872858
PMCPMC12390650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.