ArticleViruses2025
Disseminated Varicella-Zoster Virus Infection with Internal Organ Involvement: A Scoping Review of 156 Cases.
Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Isolated Sacral Herpes Zoster With Urinary Symptoms: A Case Report and a Brief Review of the Literature.Clinical case reports · 2026Article
- Disseminated herpes zoster following tear gas exposure in a patient on upadacitinib.JAAD case reports · 2026Article
- Complications of varicella and associated factors among hospitalized patients at a tertiary infectious disease hospital in Southern Vietnam.BMC infectious diseases · 2026Observational
- Concurrent Central and Autonomic Nervous System Involvement in Varicella-Zoster Virus Infection in an Immunocompetent Patient: A Case-Based Mechanistic Analysis.Infectious disease reports · 2026Article
- Article
- Varicella-Zoster Virus-Associated Esophagogastritis.Case reports in gastrointestinal medicine · 2026Article
- Research progress on abdominal epilepsy in children.Frontiers in neuroscience · 2026Review
- Article
- Disseminated Varicella Zoster and Multiorgan Failure Requiring ECMO Support in a Patient With Evans Syndrome.Case reports in critical care · 2026Article
- A Mysterious Case of Autoimmune Hepatitis Triggered by Herpes Zoster Virus Versus Drug-Induced Liver Injury.Cureus · 2026Article
- Acute Respiratory Distress Syndrome Caused by Varicella Pneumonia in an Immunocompetent Adult: A Case Report.Cureus · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Visceral disseminated varicella-zoster virus infection (VD-VZV) involves the hematogenous spread of VZV from the skin to the internal organs. Though rare, it is potentially life-threatening, predominantly affecting immunocompromised individuals. Diagnosis is often delayed due to nonspecific symptoms mimicking other viral illnesses. While the vesicular rash is a hallmark sign, it is absent in approximately 5% of cases. Visceral involvement may precede cutaneous lesions, complicate early recognition, and increase the risk of severe complications. This scoping review screened 594 articles of which 153 met the inclusion criteria, yielding 156 individual cases. Patients were predominantly male (53.8%), with a mean age of 42.3 years. The overall mortality rate was 25.0%. Multiple organs were involved in 46.1% of cases. The most frequently affected were the lungs (56%), liver (44%), heart (16%), kidneys (11%), pancreas (11%), stomach (10%), and esophagus (6%). Antivirals were administered in 89.1% of cases, while corticosteroids were used in 22.4%, with no significant impact on outcomes. Early diagnosis, achieved in 65.4% of patients, was significantly associated with survival (
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