Evidence map›Paper›PMID 40872754›Full record

ArticleViruses2025

Clinical Characteristics and Epidemiological Features of Hepatitis E Virus Infection Among People Living with HIV in Shanghai, China.

Conglin Zhao, Yuanyuan Ji, Shuai Tao, Mengxin Lu, Yi Zhang, Weixia Li, Shuangshuang Sun, Han Zhao, Weijia Lin, Yuxian Huang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Conglin ZhaoDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.ORCID 0000-0002-7814-3920
Yuanyuan JiDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Shuai TaoScientific Research Center, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Mengxin LuDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Yi ZhangDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Weixia LiDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Shuangshuang SunDepartment of Liver Disease Center, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Han ZhaoDepartment of Liver Intensive Care Unit, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Weijia LinDepartment of Hepatobiliary Medicine, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Yuxian HuangDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Qiang LiDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Chong ChenDepartment of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.
Liang ChenDepartment of Liver Disease, Shanghai Public Health Clinical Center, Fudan University, Shanghai 200437, China.

Funding

Shanghai Municipal Health Commission 2022YQ027ShenKang development center of Shanghai SHDC12020109
6 · The paper itself

Abstract

Hepatitis E virus (HEV) poses a significant public health concern, particularly among immunocompromised populations. This study aimed to investigate HEV seroprevalence, clinical characteristics, and associated risk factors in people living with HIV (PLWH) in Shanghai, China. A retrospective analysis was conducted on serum IgG and IgM antibodies specific to HEV in 670 PLWH and 464 HIV-negative health-check attendees. The overall anti-HEV seropositivity rate among PLWH was 30.15% (202/670, 95% CI 26.68-33.62), with an IgG positivity rate of 30.00% (201/670, 95% CI 26.53-33.47). IgM positivity was observed in 1.19% (8/670, 95% CI 0.59-2.39) of PLWH, and dual IgM/IgG positivity was observed in 1.04% (7/670, 95% CI 0.50-2.16) of PLWH. The seropositivity rate of anti-HEV IgG in the HIV-negative health-check attendees was 17.67% (82/464, 95% confidence interval: 14.20-21.14), with no IgM positivity, which was significantly lower than that in PLWH (χ

Indexed as

Hepatitis EHepatitis E virusHIV InfectionsAdultAgedChinaCoinfectionFemaleHepatitis AntibodiesHumansImmunoglobulin GImmunoglobulin MMaleMiddle AgedRetrospective StudiesRisk FactorsHepatitis AntibodiesImmunoglobulin GImmunoglobulin Mhepatitis E virusHIVrisk factorsseroprevalence

Identifiers

PMID40872754
PMCPMC12390178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.