Evidence map›Paper›PMID 40872694›Full record

ArticleVeterinary sciences2025

Evaluating a Targeted Antimicrobial Stewardship Program and Its Temporal Association with Resistance Trends in a Veterinary Referral Hospital.

Tomoki Motegi, Rei Fukuoka, Yuzo Tsuyuki, Dai Nagakubo, Shingo Maeda, Tomohiro Yonezawa, Ryohei Nishimura, Yasuyuki Momoi

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tomoki MotegiVeterinary Clinical Genetics and Information, Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.ORCID 0000-0002-6811-0973
Rei FukuokaVeterinary Medical Center, The University of Tokyo, Tokyo 113-8657, Japan.
Yuzo TsuyukiDivision of Clinical Laboratory, Sanritsu Zelkova Veterinary Laboratory, Tokyo 135-0011, Japan.ORCID 0000-0002-9399-909X
Dai NagakuboVeterinary Medical Center, The University of Tokyo, Tokyo 113-8657, Japan.
Shingo MaedaDepartment of Veterinary Clinical Pathobiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0003-1413-1258
Tomohiro YonezawaDepartment of Veterinary Clinical Pathobiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Ryohei NishimuraVeterinary Medical Center, The University of Tokyo, Tokyo 113-8657, Japan.
Yasuyuki MomoiDepartment of Veterinary Clinical Pathobiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is an increasing concern in companion animal practice; however, effective mitigation strategies in veterinary referral hospitals remain underexplored. This study investigated whether antimicrobial stewardship interventions guided by hospital-specific resistance patterns and prescribing data could improve resistance outcomes in a secondary care veterinary setting. Using data from 2016 to 2018 at the University of Tokyo Veterinary Medical Center, a targeted intervention was developed and implemented in early 2019, and its impact was evaluated until 2024. The intervention included Gram staining-based presumptive pathogen estimation, antibiogram-guided antimicrobial selection, clinician education, and regular feedback on prescribing practices. By 2020, overall antimicrobial use had reduced by over 50%, with marked reductions in the use of carbapenems and fluoroquinolones. By 2022, the prevalence of extended-spectrum β-lactamase-producing

Indexed as

antibiogramantimicrobial resistanceantimicrobial stewardshipextended-spectrum β-lactamasemethicillin-resistant staphylococci

Identifiers

PMID40872694
PMCPMC12390016

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.