Evidence map›Paper›PMID 40872623›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Molecular Basis of BRAF Inhibitor Resistance in Melanoma: A Systematic Review.

Ilaria Cosci, Valentina Salizzato, Paolo Del Fiore, Jacopo Pigozzo, Valentina Guarneri, Simone Mocellin, Alberto Ferlin, Sara Mathlouthi, Luisa Piccin, Mariangela Garofalo

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Autophagy in Melanoma: Molecular Mechanisms and Therapeutic Perspectives.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilaria CosciUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, 35122 Padova, Italy.ORCID 0009-0000-5998-8146
Valentina SalizzatoMedical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0003-1027-3259
Paolo Del FioreSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0002-2862-8014
Jacopo PigozzoMedical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0003-2427-8915
Valentina GuarneriMedical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
Simone MocellinSoft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.ORCID 0000-0002-9433-8445
Alberto FerlinUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, 35122 Padova, Italy.ORCID 0000-0001-5817-8141
Sara MathlouthiDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy.ORCID 0009-0006-3962-615X
Luisa PiccinMedical Oncology 2, Veneto Institute of Oncology IOV-IRCCS, 35128 Padova, Italy.
Mariangela GarofaloDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-5001-7826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BRAF inhibitors (BRAFi)BRAF mutationdrug resistanceMAPK pathwayMEK inhibitors (MEKi)melanomatargeted therapyV600E

Identifiers

PMID40872623
PMCPMC12388903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.