Evidence map›Paper›PMID 40872601›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Discovery of Small-Molecule PD-L1 Inhibitors via Virtual Screening and Their Immune-Mediated Anti-Tumor Effects.

Chunlai Feng, Yingying Ge, Siqi Wang, Mengru Li, Qiying Chen, Hangyu Dong, Mengjie Rui

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunlai FengSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Yingying GeSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Siqi WangSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.ORCID 0000-0002-1809-8857
Mengru LiSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Qiying ChenSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.ORCID 0009-0003-3602-9219
Hangyu DongSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Mengjie RuiSchool of Pharmacy, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.

Funding

National Natural Science Foundation of China 82074286Natural Science Foundation of Jiangsu Province BK20191428Open Fund Project of the NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor NHCDP2024005the Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University), Ministry of Education No numberZhenjiang Science and technology development Foundation SH2022025
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer immunotherapymolecular dockingPD-1/PD-L1 checkpointPD-L1 inhibitorpharmacophore modelingvirtual screening

Identifiers

PMID40872601
PMCPMC12388884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.