Evidence map›Paper›PMID 40872557›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

In Vitro Proof-of-Concept Study: Lidocaine and Epinephrine Co-Loaded in a Mucoadhesive Liquid Crystal Precursor System for Topical Oral Anesthesia.

Giovana Maria Fioramonti Calixto, Aylla Mesquita Pestana, Arthur Antunes Costa Bezerra, Marcela Tavares Luiz, Jonatas Lobato Duarte, Marlus Chorilli, Michelle Franz-Montan

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giovana Maria Fioramonti CalixtoDepartment of Biosciences, Piracicaba Dental School, Universidade Estadual de Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil.ORCID 0000-0003-1041-5835
Aylla Mesquita PestanaDepartment of Biosciences, Piracicaba Dental School, Universidade Estadual de Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil.
Arthur Antunes Costa BezerraDepartment of Biosciences, Piracicaba Dental School, Universidade Estadual de Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil.
Marcela Tavares LuizDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, SP, Brazil.
Jonatas Lobato DuarteDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-7276-3686
Marlus ChorilliDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-6698-0545
Michelle Franz-MontanDepartment of Biosciences, Piracicaba Dental School, Universidade Estadual de Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil.ORCID 0000-0003-0760-1389

Funding

São Paulo Research Foundation #2019/07245-5São Paulo Research Foundation #2020/03786-9
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

buccal mucosadrug delivery systemslamellar crystalline liquid systemlocal anestheticnanotechnology

Identifiers

PMID40872557
PMCPMC12389179

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.