Evidence map›Paper›PMID 40872498›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Repurposing Analysis of Nitroxoline (8-Hydroxy-5-nitroquinoline) as an Antichagasic Compound.

Carlos J Bethencourt-Estrella, Atteneri López-Arencibia, Isabel M Calero-Docina, Frieder Fuchs, Patrick Scheid, Jacob Lorenzo-Morales, José E Piñero

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos J Bethencourt-EstrellaInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203 La Laguna, Spain.ORCID 0000-0002-3486-7740
Atteneri López-ArencibiaInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203 La Laguna, Spain.ORCID 0000-0002-0675-8221
Isabel M Calero-DocinaInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203 La Laguna, Spain.
Frieder FuchsInstitute for Medical Microbiology, Immunology and Hygiene, University Hospital of Cologne, Medical Faculty, University of Cologne, 50933 Cologne, Germany.ORCID 0000-0001-7075-5378
Patrick ScheidDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56072 Koblenz, Germany.
Jacob Lorenzo-MoralesInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203 La Laguna, Spain.
José E PiñeroInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203 La Laguna, Spain.ORCID 0000-0001-6233-8224

Funding

Cabildo Insular de Tenerife 2023-2028 and the Ministerio de Sanidad, Spain CC20230222, CABILDO.23Consorcio Centro de Investigación Biomédica (CIBER) de Enfermedades Infecciosas (CIBER-INFEC); the Instituto de Salud Carlos III CB21/13/00100NextGenerationEU funds from the European Union that finance the actions of the The Resilience and Recovery FacilityPersonalized and precision medicine grant from the Instituto de Salud Carlos III MePRAM Project, PMP22/00092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chagas diseasechemotherapynitroxolineprogrammed cell death (PCD)quinolineTrypanosoma cruzi

Identifiers

PMID40872498
PMCPMC12389043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.