Evidence map›Paper›PMID 40872303›Full record

ArticlePathogens (Basel, Switzerland)2025

Converging Transmission Routes of the Highly Pathogenic Avian Influenza H5N1 Clade 2.3.4.4b Virus in Uruguay: Phylogeographic Insights into Its Spread Across South America.

Ana Marandino, Gonzalo Tomás, Yanina Panzera, Joaquín Williman, Filipe Zimmer Dezordi, Gabriel Luz Wallau, Sirley Rodríguez, Ramiro Pérez, Lucía Bassetti, Raúl Negro and 3 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ana MarandinoFacultad de Ciencias, Universidad de la República, Montevideo 11400, Uruguay.
Gonzalo TomásFacultad de Ciencias, Universidad de la República, Montevideo 11400, Uruguay.ORCID 0000-0002-0530-2046
Yanina PanzeraFacultad de Ciencias, Universidad de la República, Montevideo 11400, Uruguay.ORCID 0000-0002-7459-7810
Joaquín WillimanFacultad de Ciencias, Universidad de la República, Montevideo 11400, Uruguay.
Filipe Zimmer DezordiInstituto Aggeu Magalhães (IAM)-Fundação Oswaldo Cruz (FIOCRUZ), Recife 50670-420, Brazil.ORCID 0000-0003-3259-3456
Gabriel Luz WallauInstituto Aggeu Magalhães (IAM)-Fundação Oswaldo Cruz (FIOCRUZ), Recife 50670-420, Brazil.ORCID 0000-0002-1419-5713
Sirley RodríguezDivisión de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agriculturay Pesca, Montevideo 12100, Uruguay.
Ramiro PérezDivisión de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agriculturay Pesca, Montevideo 12100, Uruguay.
Lucía BassettiDivisión de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agriculturay Pesca, Montevideo 12100, Uruguay.
Raúl NegroDivisión de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agriculturay Pesca, Montevideo 12100, Uruguay.
Valeria UriarteDirección Nacional de Biodiversidad y Servicios Ecosistémicos (DINABISE), Ministerio de Ambiente, Montevideo 11100, Uruguay.
Carmen LeizagoyenDirección Nacional de Biodiversidad y Servicios Ecosistémicos (DINABISE), Ministerio de Ambiente, Montevideo 11100, Uruguay.
Ruben PérezFacultad de Ciencias, Universidad de la República, Montevideo 11400, Uruguay.ORCID 0000-0003-4961-4743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The highly pathogenic avian influenza H5N1 2.3.4.4b clade virus has caused widespread outbreaks across South America, primarily affecting seabirds, poultry, and marine mammals. The virus likely reached the continent through migratory birds from North America, initially spreading along the Pacific coast before advancing into Atlantic-bordering countries such as Argentina, Uruguay, and Brazil. This study investigated the dynamics of H5N1 strains in Uruguay during outbreaks from February and October 2023. We analyzed an updated South American database, including a newly sequenced viral genome from a royal tern (

Indexed as

Influenza A Virus, H5N1 SubtypeInfluenza in BirdsAnimalsBirdsDisease OutbreaksGenome, ViralHumansPhylogenyPhylogeographySouth AmericaUruguayavian influenzagenetic cladesmammal hostsphylogeographySouth Americatransmission routes

Identifiers

PMID40872303
PMCPMC12389478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.