ReviewSensors (Basel, Switzerland)2025
Real-Time, Continuous Monitoring of Tissue Chips as an Emerging Opportunity for Biosensing.
Review in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Using Organoids to Unlock the Potential of Human Torpor for Spaceflight.Current stem cell reports · 2026Article
- Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Next-generation skin wound healing related disease models with integration of immune cells.Protein & cell · 2026Review
- Regulating the Nano-Bio Interface: Converging Electrochemical and Photonic Biosensing for Wearable Diagnostics.Nano letters · 2026Review
- Lab-on-a-Chip and Microfluidics Technologies for Nano Drug Delivery.Bioengineering (Basel, Switzerland) · 2026Review
- From Electron Imbalance to Network Collapse: Decoding the Redox Code of Ischemic Stroke for Biomarker-Guided Precision Neuroprotection.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Tissue chips (TCs), otherwise known as organs-on-a-chip (OoC), organ chips (OCs), or microphysiological systems (MPS), are rapidly gaining prominence as an extension of or even replacement for traditional animal models of disease physiology. They also have recognized utility in the context of drug development: for example, data from TCs can now be submitted in place of some animal testing to the FDA. In principle, TCs are structured to allow measurement of any number of outputs that yield information about the tissue. However, to date, measurements made during experiments with TCs have been largely restricted to immunofluorescence microscopy and benchtop assays performed on media extracted from the cell culture within the device. With the development of biosensors that are sensitive and have an ever-shrinking footprint, on-board biosensing is now in the early stages of exploration. This review discusses the importance of tissue chips and the advances in sensing that will aid the complexity and utility of tissue chip research moving forward. We cover several sensing modalities, including electrical and optical sensing modes. Finally, challenges and opportunities for the future are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.