ArticleSensors (Basel, Switzerland)2025
Combined Effect of tDCS and GRASP for Upper Limb Rehabilitation in Stroke: A Clinical and Accelerometric Pilot Study.
Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Immediate excitatory effect of transcranial ultrasound intensity on the human primary motor cortex: a double-blind, sham-controlled and crossover study.Frontiers in human neuroscience · 2026Article
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Authors and funding
11 authors.
Funding
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Abstract
Upper limb (UL) impairment after stroke negatively influences stroke survivors' quality of life (QOL). This study aims to evaluate, through clinical assessment and accelerometric measures, the efficacy of anodal Transcranial Direct Current Stimulation (a-tDCS) combined with the Graded Repetitive Arm Supplementary Program (GRASP) in post-acute stroke UL rehabilitation. Subjects were enrolled if they were aged ≥18 years and had a first stroke diagnosis, UL motor impairment and adequate trunk control. The subjects underwent combined administration of intensive a-tDCS and GRASP (15 sessions/30 min each). Before and after treatment, a subgroup of subjects was evaluated through wearable accelerometers. A total of 30 subjects were included in this study (mean age 68.34 ± 14.08 years; 19 males/11 females). Medical Research Council (MRC), Hand Grip Strength (HGS), Nine-Hole Peg Test (9HPT), Box and Block Test (BBT) and Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores significantly improved after treatment. The accelerometric-derived measurements all revealed a significant increase in the affected UL activity as indicated by the Vector Magnitude value. No side effects were reported. In conclusion, an intensive a-tDCS and GRASP application proved to be effective and safe in UL rehabilitation after stroke. The association of accelerometric monitoring might be of paramount importance for the evaluation of UL recovery.
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