ReviewNutrients2025
Gentianaceae Family-Derived Bioactive Compounds-Therapeutic Values and Supporting Role in Inflammation and Detoxification.
Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Nanodelivery of Gentiopicroside for Inflammatory Skin Lesions: Insights from Psoriasis and Diabetic Foot Ulcers.International journal of nanomedicine · 2026Review
- Therapeutic Potential ofBiomedicines · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Herbs from the Gentianaceae family are widely known for their medicinal and pharmacological properties. They were used centuries ago as a part of traditional medicine in China and Tibet. This review aims to draw attention to the potential uses of gentian herbs in treating various diseases, including skin conditions, gastrointestinal and liver disorders, wound healing, rheumatoid arthritis, and diabetes. The aim of our study was to systematically summarize current knowledge about key bioactive compounds present in both roots and aerial parts-such as xanthones, iridoids, and flavonoids-and highlight their pharmacological significance. We also focused on the Gentianaceae family's usage in complementary and alternative medicine, as well as their anti-inflammatory, anti-melanogenic, anti-ischemic, anti-fibrotic, and antioxidant properties, which can be utilized in the treatment and prevention of dermatological diseases, such as skin cancers. Here, we involve ethnomedicinal knowledge with modern pharmacological data; we also highlight the scientific relevance of gentian-derived compounds in drug development. This review concludes that these species represent a promising source of natural agents, while also underlining the need for further research and conservation strategies to preserve threatened species.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.