ReviewNutrients2025
Advances in Intestinal-Targeted Release of Phenolic Compounds.
Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Integration of Laccase-like Nanozymes and Sensing Strategies for Food Quality and Safety Monitoring.Foods (Basel, Switzerland) · 2026Review
- Dietary Polyphenols as Modulators of Redox Signalling: From the Antioxidant-Pro-Oxidant Continuum to Clinical Translation (2015-2025).Current issues in molecular biology · 2026Review
- Probiotics unveiled: bridging general health benefits to the era of precision medicine.World journal of microbiology & biotechnology · 2026Review
- Hindgut-targeted delivery alpha-ketoglutarate pellets improves broiler intestinal redox and growth performance by activating uncoupling protein 2.Poultry science · 2026Article
- Effects of Different Commercial Formulations of Tannic Acid Added at an Equal Inclusion Rate on Intestinal Health and Microbial Flora in Yellow-Feathered Broilers.Animals : an open access journal from MDPI · 2026Article
- Phenolic Acids and Their Derivatives in Tea: Chemical Diversity, Processing Changes, Sensory Contributions, and Health Implications-A Comprehensive Review.Comprehensive reviews in food science and food safety · 2026Review
- Preparation and Stability Study of Co-Encapsulated Particles of Curcumin or Quercetin withFoods (Basel, Switzerland) · 2026Article
- Metabolomic Characterization of Baby Spinach Phenolics Transformation During Gastrointestinal Digestion and Microbiome-Mediated Metabolism.Foods (Basel, Switzerland) · 2026Article
- Engineered live bacteria for liver diseases and gut-liver axis disorders: from genetic modification to advanced delivery systems.Journal of nanobiotechnology · 2026Review
- Encapsulation of Bee Pollen Phenolics with β-Cyclodextrin: Effects on Antioxidant Activity, Antimicrobial Properties, and Digestive Stability.Foods (Basel, Switzerland) · 2026Article
- Probiotics and Phytoantioxidants as Emerging Neuroprotective Strategies: Bridging the Therapeutic Gap in Open Heart Surgery-Induced Brain Injury.Biomedicines · 2026Review
- Punicalagin is the key pomegranate polyphenol inhibiting gut microbial trimethylamine (TMA) production from L-carnitine in anFood & function · 2026Article
- Comparative In Vitro Evaluation of Buccal Films, Microcapsules, and Liposomal Systems for Naringin andPharmaceutics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Phenols are natural compounds with considerable bioactivities. However, the low bioavailability and chemical instability of phenols limit their biological functions. This review summarizes recent progress in phenol delivery systems that account for the specific physiological conditions of the gastrointestinal tract. It focuses on the delivery materials for intestinal targeting and the synergistic benefits of co-encapsulating phenols with other functional ingredients. To achieve targeted release of phenols in the digestive tract, factors such as pH, digestive enzymes, and gut microbiota should be fully considered in delivery system designing. Materials like chitosan, sodium alginate, pectin, and guar gum offer effective protection and targeted delivery of phenols due to their pH sensitivity and enzyme-degradable properties. Co-delivery systems that combine phenols with carotenoids or probiotics improve the functional properties of phenols, such as antioxidant activity, anti-inflammatory effect, and regulation of gut microbiota. Probiotics can enhance phenolic compound absorption and probiotic survival in a phenolic-probiotic co-encapsulation system through debonding, bioconversion, and synergistic effects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.