Evidence map›Paper›PMID 40871572›Full record

ArticleMolecules (Basel, Switzerland)2025

The Chelating Abilities of Tertiary Amines with N-O-Donors Towards Cu(II) Ions and the Catalytic Properties of the Resulting Complexes.

Martina Zonzin, Martina Chianese, Andrea Squarcina, Degnet Melese Dereje, Ambra Campofelice, Alessia Da Fermo, Federica Belluti, Nadia Marino, Filip Dębicki, Aleksandra Kotynia and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Martina ZonzinDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy.
Martina ChianeseDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy.
Andrea SquarcinaDepartment of Chemistry, Ludwig-Maximilians Universität (LMU), Butenandtstr, 5-13, 81377 München, Germany.ORCID 0000-0003-1770-586X
Degnet Melese DerejeDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy.ORCID 0000-0002-8951-8433
Ambra CampofeliceDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy.
Alessia Da FermoDepartment of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.ORCID 0009-0001-3985-1692
Federica BellutiDepartment of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.ORCID 0000-0002-6365-5579
Nadia MarinoDepartment of Chemistry and Chemical Technologies, University of Calabria, Via P. Bucci 14/c, 87036 Arcavacata Di Rende, CS, Italy.ORCID 0000-0002-7038-9715
Filip Dębicki4TH Military Clinical Hospital, Weigla 5, 53-114 Wroclaw, Poland.ORCID 0009-0000-6100-4660
Aleksandra KotyniaDepartment of the Basic Chemical Sciences, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-0730-8975
Aleksandra MarciniakDepartment of the Basic Chemical Sciences, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-2225-7897
Justyna BrasuńDepartment of the Basic Chemical Sciences, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Mauro CarraroDepartment of Chemical Sciences, University of Padova, Via F. Marzolo 1, 35131 Padova, Italy.ORCID 0000-0002-1194-6147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress, driven by excess reactive oxygen species (ROS), is a key factor in the progression of neurodegenerative diseases like Alzheimer's disease (AD). In this context, copper dysregulation can also contribute to this imbalance, being responsible for enhanced ROS production, so that copper scavenging has been investigated as a possible therapeutic strategy. This study investigates the behavior of two isostructural ligands, featuring an N

Indexed as

AminesChelating AgentsCoordination ComplexesCopperAlzheimer DiseaseAmyloid beta-PeptidesAntioxidantsCatalysisHumansHydrogen-Ion ConcentrationIonsLigandsReactive Oxygen SpeciesAminesAmyloid beta-PeptidesAntioxidantsChelating AgentsCoordination ComplexesCopperIonsLigandsReactive Oxygen Speciesamyloid aggregationantioxidantschelatorscopper complexesN3O donors

Identifiers

PMID40871572
PMCPMC12388300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.