Evidence map›Paper›PMID 40871507›Full record

ArticleMolecules (Basel, Switzerland)2025

Synthesis and Properties of Silver Nanoparticles Functionalized with β-Cyclodextrin and Their Loading with Lupinine and Its Acetyl Derivatives.

Serik D Fazylov, Zhangeldy S Nurmaganbetov, Oralgazy A Nurkenov, Akmaral Z Sarsenbekova, Olzhas T Seilkhanov, Roza B Seidakhmetova, Anel Z Mendibayeva, Ryszhan Y Bakirova, Zainulla M Muldakhmetov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Lupinine as an Acetylcholinesterase Inhibitor fromMolecules (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Serik D FazylovLaboratory of Synthesis of Biologically Active Substances, Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0002-4240-6450
Zhangeldy S NurmaganbetovLaboratory of Synthesis of Biologically Active Substances, Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0002-0978-5663
Oralgazy A NurkenovLaboratory of Synthesis of Biologically Active Substances, Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0003-1878-2787
Akmaral Z SarsenbekovaDepartment of Physical and Analytical Chemistry, Karaganda University of the Name of E.A. Buketov, Karaganda 100074, Kazakhstan.ORCID 0000-0002-8951-3616
Olzhas T SeilkhanovLaboratory of Engineering Profile NMR-Spectroscopy, Sh. Ualikhanov Kokshetau University, Kokshetau 120000, Kazakhstan.
Roza B SeidakhmetovaDepartment of Clinical Pharmacology and Evidence-Based Medicine, Karaganda Medical University, Karaganda 100012, Kazakhstan.
Anel Z MendibayevaLaboratory of Synthesis of Biologically Active Substances, Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.ORCID 0000-0001-6123-3340
Ryszhan Y BakirovaDepartment of Internal Diseases, Karaganda Medical University, Karaganda 100012, Kazakhstan.
Zainulla M MuldakhmetovLaboratory of Synthesis of Biologically Active Substances, Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AР23487712
6 · The paper itself

Abstract

This study presents the results of a study of the synthesis and properties of 2-hydroxy-β-cyclodextrin functionalized by silver nanoparticles and its loading with a bioactive component. As a reducing agent and stabilizer, 2-Hydroxy-β-cyclodextrin (2gβCD) was used in the production of silver nanoparticles. The use of 2gβCD-AgNPs in loading molecules of the plant alkaloid lupinine (Lup) and its acetyl derivative (Lac) with bactericidal properties were studied. The formation of Lup-2gβCD-AgNPs and Lac-2gβCD-AgNPs was confirmed by UV spectroscopy and X-ray diffraction spectroscopy (XRD). Transmission electron microscopy (TEM) showed that the synthesized AgNPs had a spherical shape.

Indexed as

beta-CyclodextrinsMetal NanoparticlesPentacyclic TriterpenesSilverAnimalsAnti-Bacterial AgentsMiceMicrobial Sensitivity TestsSpectroscopy, Fourier Transform InfraredX-Ray DiffractionAnti-Bacterial Agentsbeta-CyclodextrinsPentacyclic TriterpenesSilver2-hydroxypropyl-β-cyclodextrinanalgetic activitiesbactericidalcytotoxiclupininelupinyl acetatenanocompositesilver nanoparticles

Identifiers

PMID40871507
PMCPMC12388491

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.