Evidence map›Paper›PMID 40871445›Full record

ArticleMicroorganisms2025

Predictive Microbial Markers Distinguish Responders and Non-Responders to Adalimumab: A Step Toward Precision Medicine in Ulcerative Colitis.

Shaghayegh Baradaran Ghavami, Arfa Moshiri, Carola Bonaretti, Maryam Farmani, Margherita Squillario, Eddi Di Marco, Shabnam Shahrokh, Hedieh Balaii, Maria Valeria Corrias, Mirco Ponzoni and 2 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shaghayegh Baradaran GhavamiIBD Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran.
Arfa MoshiriExperimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0001-8030-0190
Carola BonarettiMolecular Diagnostics, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
Maryam FarmaniIBD Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran.ORCID 0000-0001-9941-733X
Margherita SquillarioIRCCS Ospedale Policlinico San Martino, 16131 Genova, Italy.ORCID 0000-0002-6612-3383
Eddi Di MarcoCentral Laboratory, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
Shabnam ShahrokhIBD Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran.
Hedieh BalaiiIBD Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran.
Maria Valeria CorriasExperimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-7316-0772
Mirco PonzoniExperimental Therapies in Oncology, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-6164-4286
Amir SadeghiIBD Department, Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran.
Roberto BiassoniMolecular Diagnostics, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-4365-8166

Funding

Compagnia di San Paolo 2019.0880-ID ROL 32612 (RB)Italian Ministry oh Health Ricerca Corrente to MPMinistry of Health Ricerca Corrente to RB
6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic, relapsing inflammatory disease of the colon, often associated with gut microbial dysbiosis. Although anti-TNF-α agents, such as Adalimumab (Cinnora

Indexed as

Mayo scoremucosal metagenomicsstool metagenomicsTNF alpha inhibitors therapyulcerative colitis

Identifiers

PMID40871445
PMCPMC12388438

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.