Evidence map›Paper›PMID 40871378›Full record

ArticleMicroorganisms2025

Quantification and Comparison of Different Biofilm Components from Methicillin-Susceptible

Marta Díaz-Navarro, Antonio Benjumea, Andrés Visedo, Patricia Muñoz, Javier Vaquero, Francisco Chana, María Guembe

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marta Díaz-NavarroDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0002-1572-8040
Antonio BenjumeaDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Andrés VisedoDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Patricia MuñozDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0001-5706-5583
Javier VaqueroInstituto de Investigación Sanitaria Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0002-8785-2278
Francisco ChanaDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0002-1227-1874
María GuembeDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.ORCID 0000-0002-7607-5848

Funding

Comunidad de Madrid PEJD-2021-TL/BMD-21113Fundación Mutua Madrileña FMM24/01IiSGM 2022-PI-II-COOPTR-01Instituto de Salud Carlos III FI22/00022Instituto de Salud Carlos III MSII18/00008Instituto de Salud Carlos III PI21/00344the SEROD FS24/01
6 · The paper itself

Abstract

As we previously demonstrated that tranexamic acid (TXA), an antifibrinolytic, showed an antibacterial effect alone and in combination with vancomycin and gentamicin, we now wanted to analyze its own efficacy using new, different fluorescent staining reagents that target different components of the biofilm matrix and compare which one quantifies biofilm reduction better. A 10

Indexed as

biofilmCLSMDNAextracellular matrixpolysaccharidesproteinsstainingStaphylococcus aureustranexamic acid

Identifiers

PMID40871378
PMCPMC12388762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.