Evidence map›Paper›PMID 40871172›Full record

ArticlePolymers2025

Advanced Electrospun Chitosan-(Polylactic Acid)-(Silver Nanoparticle)-Based Scaffolds for Facilitated Healing of Purulent Wounds: A Preclinical Investigation.

Yevhen Samokhin, Yuliia Varava, Anna Butsyk, Roman Moskalenko, Yevheniia Husak, Bohdan Dryhval, Valeriia Korniienko, Ihor Zhyvotovskyi, Vyacheslav Kukurika, Artem Shmatkov and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yevhen SamokhinBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.ORCID 0000-0001-7883-0491
Yuliia VaravaBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.ORCID 0000-0002-1007-3743
Anna ButsykUkrainian-Swedish Research Center SUMEYA, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.ORCID 0000-0002-0019-025X
Roman MoskalenkoDepartment of Pathology, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.ORCID 0000-0002-2342-0337
Yevheniia HusakFaculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland.
Bohdan DryhvalBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.
Valeriia KorniienkoBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.
Ihor ZhyvotovskyiBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.
Vyacheslav KukurikaBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.
Artem ShmatkovBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.
Agne RamanaviciuteDepartment of Nanotechnology, Centre for Physical Sciences and Technology, Sauletekio Av. 3, LT-10257 Vilnius, Lithuania.
Rafal BanasiukNanoWave Ltd., 02-676 Warsaw, Poland.ORCID 0000-0002-3774-1545
Maksym PogorielovBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.ORCID 0000-0001-9372-7791
Arunas RamanaviciusDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0002-0885-3556
Viktoriia KorniienkoBiomedical Research Centre, Medical Institute, Sumy State University, 116, Kharkivska St., 40007 Sumy, Ukraine.

Funding

HORIZON-Europe MSCA-SE-2021 101086441
6 · The paper itself

Abstract

Biomaterials modified by antibacterial substances, including nanoparticles, open new opportunities for the effective treatment of infected wounds. Unfortunately, most publications focused only on experiments in vitro, with limited understanding of their potential for the clinic. This study evaluates the effectiveness in vivo of electrospun chitosan/polylactic acid (Ch/PLA) membranes enriched with silver nanoparticles (AgNPs) for purulent wound treatment. The composite biomaterial integrates chitosan's biocompatibility and antimicrobial activity with PLA's structural integrity, while AgNPs enhance antibacterial efficacy against major wound pathogens, including

Indexed as

antimicrobial biomaterialschitosanelectrospinningpolylactic acidpurulent woundssilver nanoparticleswound healing

Identifiers

PMID40871172
PMCPMC12389543

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.