Evidence map›Paper›PMID 40871088›Full record

ReviewPharmaceutics2025

Chitosan Nanoparticles Loaded with Polyphenols for Cosmeceutical Applications: A State-of-the-Art Review.

Valeria Gaetano, Agnese Gagliardi, Elena Giuliano, Emanuela Longo, Donato Cosco

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Phytochemistry and Biological Effects of theAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valeria GaetanoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "S Venuta", 8100 Catanzaro, Italy.ORCID 0009-0006-0491-846X
Agnese GagliardiDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "S Venuta", 8100 Catanzaro, Italy.
Elena GiulianoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "S Venuta", 8100 Catanzaro, Italy.
Emanuela LongoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "S Venuta", 8100 Catanzaro, Italy.
Donato CoscoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, Campus Universitario "S Venuta", 8100 Catanzaro, Italy.ORCID 0000-0002-4898-0365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology has been widely employed in the field of cosmeceuticals, promoting the development of innovative cosmetic formulations characterized by notable pharmacological activity. The use of nanocosmeceuticals allows for better skin penetration of active compounds, their controlled release over time, and greater physico-chemical stability. Chitosan nanoparticles have generated significant interest in the scientific community as dermal and transdermal delivery systems for natural compounds. In particular, the encapsulation of polyphenols within chitosan nanosystems has been proposed as a method to enhance the effectiveness of bioactives in cosmeceutical formulations. This review discusses the most relevant scientific literature on the topic, with particular attention to studies published in recent years. Chitosan-based nanosystems improve the stability, bioavailability, and skin compatibility of polyphenols, offering promising solutions for the prevention and treatment of skin disorders due to their antioxidant and anti-inflammatory properties. This review provides a comprehensive update on the development of chitosan nanoparticles containing polyphenols and their potential clinical applications, highlighting the role of these systems as nanocosmeceuticals.

Indexed as

chitosancosmeceuticalpolyphenolsskin diseasestopical administration

Identifiers

PMID40871088
PMCPMC12389162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.