Evidence map›Paper›PMID 40870980›Full record

ArticlePharmaceutics2025

Enhancing the Solubility and Oral Bioavailability of Trimethoprim Through PEG-PLGA Nanoparticles: A Comprehensive Evaluation of In Vitro and In Vivo Performance.

Yaxin Zhou, Guonian Dai, Jing Xu, Weibing Xu, Bing Li, Shulin Chen, Jiyu Zhang

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaxin ZhouKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, China.
Guonian DaiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, China.
Jing XuKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, China.
Weibing XuCollege of Science, Gansu Agricultural University, Lanzhou 730070, China.
Bing LiKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, China.
Shulin ChenCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
Jiyu ZhangKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou 730050, China.

Funding

the Innovation Project of the Chinese Academy of Agricultural Sciences CAAS-ASTIP-2014-LIHPSthe Key Research and Development Program of Gansu Province 24YFNA017the Lanzhou Youth Science and Technology Talent Innovation Project 2023-QN-73the Lanzhou Youth Science and Technology Talent Innovation Project 2024-QN-141
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bioavailabilitynanoparticlesPEG-PLGApharmacokineticstrimethoprim

Identifiers

PMID40870980
PMCPMC12389140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.