Evidence map›Paper›PMID 40870791›Full record

ArticleFoods (Basel, Switzerland)2025

Development of Alginate-Pullulan Capsules for Targeted Delivery of Herbal Dietary Supplements in Functional Fermented Milk Products.

Alibek Muratbayev, Berik Idyryshev, Aitbek Kakimov, Aigerim Bepeyeva, Madina Jumazhanova, Marzhan Tashybayeva, Gulmira Zhumadilova, Nazerke Muratzhankyzy, Zhadyra Imangaliyeva, Aray Bazanova

Abstract read
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In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alibek MuratbayevResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Berik IdyryshevResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Aitbek KakimovResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Aigerim BepeyevaResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Madina JumazhanovaResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Marzhan TashybayevaResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Gulmira ZhumadilovaResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Nazerke MuratzhankyzyResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.
Zhadyra ImangaliyevaFaculty of Food Technology, Almaty Technological University, 100 Tole bi Str., Almaty 050010, Kazakhstan.ORCID 0000-0003-3419-7852
Aray BazanovaResearch School of Food Engineering, Shakarim University, 20A Glinki Street, Semey 071412, Kazakhstan.

Funding

Ministry of Science and Higher Education of the Republic of Kazakhstan AP22686708
6 · The paper itself

Abstract

The present study develops and optimizes a jet-cutting encapsulation method using a laboratory-scale encapsulator to incorporate herbal dietary supplements into fermented milk products. Sodium alginate and pullulan were selected as core and coating polymers, respectively, after rheological screening demonstrated that 1% alginate (η ≈ 350-450 Pa·s at 22-25 °C) and 2% pullulan (η ≈ 400 Pa·s at 25-30 °C) provide a balance between atomization, shell integrity, and fluidity. Under optimized conditions, capsules of 1.00 ± 0.05 mm diameter and high sphericity (aspect ratio 1.08 ± 0.03) were produced. In vitro gastrointestinal simulation confirmed capsule stability in simulated gastric fluid (pH 2.0) and complete disintegration within 120 min in simulated intestinal fluid (pH 7.2). Inclusion of 8% (

Indexed as

encapsulationfermented milk beveragegastrointestinal releasemicrocapsule morphologypullulan coatingrheological propertiessodium alginate

Identifiers

PMID40870791
PMCPMC12385854

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.