Evidence map›Paper›PMID 40870713›Full record

ArticleFoods (Basel, Switzerland)2025

Low-Dose, Post-Storage Dancong Tea Attenuates Hydroalcohol-Induced Gastric Damage via Modulation Antioxidant and Anti-Inflammatory Pathways.

Huanwei Jian, Ruohong Chen, Lingli Sun, Qiuhua Li, Junxi Cao, Xingfei Lai, Zhenbiao Zhang, Suwan Zhang, Mengjiao Hao, Shili Sun and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Huanwei JianGuangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou 510642, China.
Ruohong ChenTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Lingli SunTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Qiuhua LiTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Junxi CaoTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Xingfei LaiTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Zhenbiao ZhangTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Suwan ZhangTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Mengjiao HaoTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.
Shili SunTea Research Institute, Guangdong Academy of Agricultural Sciences/Guangdong Provincial Key Laboratory of Tea Plant Resources Innovation & Utilization, Guangzhou 510640, China.ORCID 0000-0003-3062-1185
Zhongzheng ChenGuangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou 510642, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2022A1515110190, 2023A1515010264, 2024A1515010696Guangzhou Science and Technology Plan Projects 20212100005, 202201011455, 2023E04J0781Modern Agricultural Industrial Technology System CARS-19Qingyuan Science and Technology Plan Projects 2021ZDZX002Special fund for scientific innovation strategy-construction of high level Academy of Agriculture Science R2022PY-QY010Special fund project for introduction of scientific and technological talents of Guangdong Academy of Agricultural Sciences R2021YJ-YB3014The project of guangdong province rural science and technology commissioner stationed in the village and town KTP20210090
6 · The paper itself

Abstract

Dancong tea is a representative type of oolong tea typically stored for over six months before sale to reduce gastrointestinal irritation. The effects and mechanisms of this storage on gastrointestinal damage remain unclear. Therefore, this study investigated hydrochloric acid and ethanol (HCl/EtOH)-induced gastric injury in mice. The results indicate that six-month-stored Dancong tea (OldT) alleviated gastric injury at low doses but showed no protective effect at high doses; in fact, high-dose OldT exacerbated injury. In contrast, fresh tea (NewT) aggravated gastric injury at both low and high doses. Hematoxylin and eosin (H&E) staining revealed that low-dose OldT significantly attenuated gastric histopathological injury. Mechanistically, low-dose OldT reduced injury via antioxidant and anti-inflammatory pathways (Nrf-2/HO-1 activation and NF-κB inhibition), and inhibiting lipid peroxidation, reactive oxygen species (ROS), nitric oxide (NO), and inflammatory mediators (iNOS, COX-2, IL-6, TNF-α). These findings suggest that storage reduces the gastrointestinal irritant properties of fresh Dancong tea, providing a scientific basis for industrial practice and guiding consumption.

Indexed as

antioxidantgastric injuryinflammatorylow-dosenew teastored tea

Identifiers

PMID40870713
PMCPMC12385579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.